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Textbook of Stroke Medicine
Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.
The Skin and Gene Therapy
Basic Aspects.- 1 The Epidermal Barrier and Strategies for Surmounting It: An Overview.- 2 Stem Cells, Differentiation and Renewal Kinetics of Keratinocytes: Implications for Cutaneous Gene Therapy.- 3 Relevant Animal Models for Skin Gene Therapy.- 4 Nonviral Gene Transfer into the Skin.- 5 Safety and Pharmacokinetics of Naked Plasmid DNA: Studies on Dissemination and Ectopic Expression.- 6 Uptake of DNA by Keratinocytes.- Treatment of Skin Diseases.- Gene Therapy of Inherited Skin Diseases.- Gene Transfer Strategies in Tissue Repair.- Systemic Effects of Skin Gene Therapy.- The Use of Skin-Directed Gene Therapy in the Treatment of Systemic Diseases.- Keratinocyte Gene Therapy Using Cytokine Genes.- Genetic Vaccination Using the Skin.- Principles of Genetic Immunization.- Systematic Modulation of Immune Responses by CpG DNA.- Genetic and Dendritic Cell Vaccination as a Novel Therapy for Melanoma.- Molecular Strategies Interfering with Tumor Progression of Melanoma and Improving Anti-Tumor Immunity.- Prophylactic and Therapeutic DNA Vaccines Against Infectious Diseases.
Noninvasive Mechanical Ventilation
Noninvasive mechanical ventilation is an effective technique for the management of patients with acute or chronic respiratory failure. This comprehensive and up-to-date book explores all aspects of the subject. The opening sections are devoted to theory and equipment, with detailed attention to the use of full-face masks or helmets, the range of available ventilators, and patient-ventilator interactions. Clinical applications are then considered in depth in a series of chapters that address the use of noninvasive mechanical ventilation in chronic settings and in critical care, both within and outside of intensive care units. Due attention is also paid to weaning from conventional mechanical ventilation, potential complications, intraoperative applications, and staff training. The closing chapters examine uses of noninvasive mechanical ventilation in neonatal and pediatric care. This book, written by internationally recognized experts, will be an invaluable guide for both clinicians and researchers.
Spoken Language Processing
Remarkable progress is being made in spoken language processing, but many powerful techniques have remained hidden in conference proceedings and academic papers, inaccessible to most practitioners. In this book, the leaders of the Speech Technology Group at Microsoft Research share these advances -- presenting not just the latest theory, but practical techniques for building commercially viable products.KEY TOPICS: Spoken Language Processing draws upon the latest advances and techniques from multiple fields: acoustics, phonology, phonetics, linguistics, semantics, pragmatics, computer science, electrical engineering, mathematics, syntax, psychology, and beyond. The book begins by presenting ...
Music after the Fall
"...the best extant map of our sonic shadowlands, and it has changed how I listen."—Alex Ross, The New Yorker "...an essential survey of contemporary music."—New York Times "…sharp, provacative and always on the money. The listening list alone promises months of fresh discovery, the main text a fresh new way of navigating the world of sound."—The Wire 2017 Music Book of the Year—Alex Ross, The New Yorker Music after the Fall is the first book to survey contemporary Western art music within the transformed political, cultural, and technological environment of the post–Cold War era. In this book, Tim Rutherford-Johnson considers musical composition against this changed backdrop, pl...
Katerina's Windows
"Examines 58 letters written by Katerina Lemmel, a wealthy Nuremberg widow, who in 1516 entered the abbey of Maria Mai in south Germany, and rebuilt the monastery using her own resources and the donations she solicited from relatives"--Provided by publisher.
Trends in Deep Learning Methodologies
Trends in Deep Learning Methodologies: Algorithms, Applications, and Systems covers deep learning approaches such as neural networks, deep belief networks, recurrent neural networks, convolutional neural networks, deep auto-encoder, and deep generative networks, which have emerged as powerful computational models. Chapters elaborate on these models which have shown significant success in dealing with massive data for a large number of applications, given their capacity to extract complex hidden features and learn efficient representation in unsupervised settings. Chapters investigate deep learning-based algorithms in a variety of application, including biomedical and health informatics, comp...
Imperfection and Defeat
Literature is defined in a challenging way as the "science" of imperfection and defeat, or else as a type of discourse that deals with defeat, loss, uncertainty in social life, by contrast with virtually all disciplines (hard sciences or social sciences) that affirm certainties and wish to convince us of truths. If in real history most constructive attempts end up in failure, it follows that we ought to have also a field of research that examines this diversity of failures and disappointments, as well as the alternative options to historical evolution and progress. Thus literature serves an indispensable role: that of gleaning the abundance of past existence, the gratuitous and the rejected being placed here on an equal level with the useful and the successful.This provocative and unusual approach is illustrated in chapters that deal with the dialectics between literary writing and such fields as historical writing, or religious discourses, and is also illustrated by the socio-historical development of East-Central Europe.
Critical Care of the Stroke Patient
New and groundbreaking therapeutic options for the critical care of patients with cerebrovascular disease have improved patient management, minimized morbidity, reduced in-patient care, improved quality of life, and had a positive economic impact on health service provision. This volume integrates these approaches and suggests the best therapy option for all cerebrovascular conditions. The early chapters of the book focus on monitoring techniques and interventions. Subsequent sections address the critical care of a wide range of cerebrovascular diseases: ischemic stroke, intracranial hemorrhage, subarachnoid hemorrhage, arteriovenous malformations, cerebral venous thrombosis and traumatic injury. The editors and authors are internationally recognized experts in their field, and the text is supplemented by tables and illustrations to demonstrate important clinical findings. This book will meet the needs of stroke physicians, neurologists, neurosurgeons, neurointensivists and interventional neuroradiologists seeking to maximize positive outcomes for their patients.
