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The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration. Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.
In the past, neo-tribalism in a Western context has been feared as leading to blindness or irrationality. In today's business world, tribalism represents a conscious separation of the individual ego for the good of the community. This is the key to understanding the success of the most innovative businesses in the 21st century.
Aims to increase awareness about the specific circumstances of LGBT (lesbian, gay, bisexual, and transgender) diversity. Based on a wide array of literature this volume provides a global vision of this reality, explaining the evolution of homosexuality during history and reasons why it has been considered a sin, an illness and a crime.
This totally reworked book combines two previous books with material on networking. It is a complete guide to programming and interfacing the 8051 microcontroller-family devices for embedded applications.
This is the first of its kind in its topical coverage of the developments and prospects of Islamic finance education at Western higher education. Intended to establish itself as a unique reference for academics and researchers this book gives an insight into ethics and values in curricula development at business schools and in finance departments.
This 1971 text was the first critical edition of La fianza satisfecha, a play of disputed authorship dating from the Golden Age of Spanish literature. The hero of la fianza satisfecha, Leonido, is represented as a perverse monster who, in the last act, finally embraces Christianity and repents his sins.
A dictionary for a world whose cities are linked by fiber optic cables and whose citizens are virtually global, a world where airports are meeting places and meetings take place via web conference, the Metapolis Dictionary of Advanced Architecture in the Information Age.
Mechanical ventilation and weaning is one of the most common procedures carried out in critically ill patients. Appropriate management of these patients is of paramount importance to improve the outcome in terms of both morbidity and mortality. This book offers the physiological and clinical basis required to improve the care delivered to patients undergoing mechanical ventilation.