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This third edition is an update on every conceivable aspect of the modern-day management of contact dermatitis. Both irritant and allergic contact dermatitis are covered clearly and comprehensively, special emphasis being given to occupational aspects as well as to prevention, diagnosis and treatment. The Textbook also covers epidemiology, the computerization of patch test data and patient information systems, noninvasive bioengineering measurement techniques, methods of skin testing other than patch testing, the histopathology of both irritant and all ergic contact dermatitis, and subjective reactions.
10. 1. 1. 1 The Purpose of Patch Testing Patch testing is a well-established method of diagnosing allergic contact dermatitis, a delayed type of hypersensitivity (type IV reaction). Patients with a history and clinical picture of contact dermatitis are reexposed to the suspected allergens under controlled conditions to verify the diagnosis. Besides testing patients with hand, arm, face or leg eczema (stasis dermatitis), testing of other types of eczema (atopic, seborrhoeic dermatitis, nummular eczema) is sometimes indicated, especially when the dermatologist suspects contact allergy to prescribed topical medicaments and their vehicles. Apart from its use to confirm a suspected allergic contact dermatitis, the patch test procedure can also be used before recommending alternative corti costeroids, skin care products, cosmetics, gloves, etc. in a particular patient. If the patient does not react to the alternatives tested, it is very unlikely that she or he will react to the products in ordinary use. 10. 1. 1.2 Standardization The first patch tests according to present principles were carried out in 1895 [1], but were preceded by some preliminary experiments [2] (see Chap. 1).
It is an unusual event for a textbook covering such a national and international networks and the use of highly specialized field as contact dermatitis to be standardized methodology, a highly differentiated published in its fourth edition within a time period picture can now be painted; we know the major p- of 13 years. When the European and Environmental fessions at risk, as well as the influences of age and Contact Dermatitis Research Group was founded in various cofactors. This is a solid basis for preventive 1985,one of the major goals was to edit a textbook of measures. A new allergen, described in one center, high scientific standard written by renown experts can now be tested on a la...
This text offers an overview of research and comment on the detrimental effects of ultraviolet radiation, chemical agents and other substances in the environment and will be of wide interest to dermatologists, toxicologists, environmental scientists, pharmacologists, oncologists and microbiologists.
Allergic skin diseases belong to the most common dermatoses. This book deals with fundamental (in particular immunological aspects) as well as clinical symptoms and therapeutic strategies of the allergic skin diseases. Cells involved in the pathomechanisms of allergic skin disease are described in individual chapters. The allergic skin diseases which will be discussed are atopic dermatitis, being the chronic inflammatory skin disease with the highest prevalence, allergic contact dermatitis with special focus on contact dermatitis from cosmetics, being the most frequent cause of contact dermatitis and occupational contact dermatitis. The broad ethiology of urticaria and the value of several therapeutic strategies will be explained. The chapter on drug allergy will deal with the variety of symptoms and the difficulties concerning in vitro and in vivo diagnosis. The book is of great interest to clinicians working in the field of dermatology, allergology, pediatrics and even general practitioners...
Dry Skin and Moisturizers: Chemistry and Function presents new information relating to skin biochemistry and pathological changes seen in various dry skin disorders. The book examines the pharmacology of ingredients in moisturizing preparations, providing a broad overview of formulations as well as detailed information on ingredients. Featuring contributions from leading researchers from around the world, the book also outlines general principles for testing and evaluation of effects on the skin, with particular emphasis on safety assessment. This comprehensive book is divided into five parts. Part I, Dry Skin and Moisturizers, offers an introduction to this fascinating topic, while Part II,...
A highly practical approach to occupational dermatoses combined with the skill and experience of specialists in clinical and experimental dermatology. Great care is taken throughout to provide the information urgently needed for daily patient management, with concise tables, algorithms, and figures on how to optimise the diagnostic procedure for high-quality patient care and expert opinion. This handbook provides the relevant job descriptions, job-specific diagnostic algorithms and a detailed description of allergens and irritants such that readers can master even difficult and unusual problems in occupational dermatology.
Aromas are an integral part of our civilised society. They are not only used in fine perfumes, but also in numerous other articles with which we have daily contact. Another new development has been the agricultural use of aromas as a "biological weapon" to combat insects and other pests. In the field of dermatology, aromas are today among the most frequent sensitizers and may trigger allergic contact eczemas. This volume presents numerous aspects of the topic for the first time in comprehensive form. In an introduction, the chemistry of frequently used aroma components is described, together with the art of perfume composition that has been refined over the centuries. In a chapter on neuropharmacology, the mechanisms of scent recognition are described in detail.
This state-of-the-art reference provides comprehensive multidisciplinary coverage of the most recent information on cosmetic ingredients, finished products, target organs, delivery systems, and current technology in safety, toxicology, and dermatological testing. Discussing modern innovations such as active cosmetics for the hair, skin, and