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Taurine 5
The Taurine Symposium- "Taurine: Beginning the 21'' Century"- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first t...
Reversible Ligand Binding
Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand Binding: Theory and Experiment discusses the physical background of protein-ligand interactions—providing a comprehensive view of the various biochemical considerations that govern reversible, as well as irreversible, ligand binding. Special consideration is devoted to enzymology, a field usually treated separately from ligand binding, but actually governed by identical thermodynamic relationships. Attention is given to the design of the experiment, which aids in showing clear evidence of biochemical features that may otherwise escape notice. Classical exper...
Red Blood Cell Aging
The mammalian erythrocyte is a very suitable model for the study of aging at the cellular and molecular level. It is not only a matter of apparent simplicity in terms of biochemistry, biophysics and physiology but more likely this cell offers a great possibility for elucidating some basic problems in the process of aging. In fact, nowadays, it is possible to follow individual cells all along their life span in circulation, it is possible to obtain these cells when young, middle aged or old and it is possible to obtain cells from individuals of defined ages and transfuse them into compatible recipients to investigate the role of the environment where the cell lives, and finally it is possible...
Ibss: Anthropology: 1999
IBSS is the essential tool for librarians, university departments, research institutions and any public or private institution whose work requires access to up-to-date and comprehensive knowledge of the social sciences.
Mitochondria and Cancer
Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.
Cellular Respiration and Carcinogenesis
Cellular Respiration and Carcinogenesis presents leading experts in the field as it informs the reader about both basic and recent research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This masterfully compiled text offers the reader a fundamental understanding about how oxygen sensing and/or availability, programmed cell death, immune recognition and response and glucose metabolism are intimately linked with the two major mechanism or pathways of cellular respiration; oxidative phosphorylation and glycolysis. The editors and contributing authors proficiently and unequivocally address the effects of dysfuncti...
The SAGE Encyclopedia of Stem Cell Research
The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This ...
