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The area of polyamines is presented in this useful, two-volume publication. Basic information describing the role of polyamines in the processes of growth and differentiation is given. Also included are data on the regulation of polyamine biosynthesis and metabolism and their interactions with nucleic acids. Several chapters are devoted to the role of polyamines in various aspects of plant biology, with a special emphasis on their participation in the response of plants to extreme environments. Special attention is given to the use of inhibitors of polyamine biosynthesis as potential antitumor and antiproliferative agents. Additionally, progress in the molecular biology and genetic engineering of genes coding for polyamine biosynthetic enzymes is described. Cancer researchers, biologists, geneticists, biochemists, physiologists, and clinicians will find this volume indispensable.
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This book provides up-to-date information on various inherited neurological disorders, presenting 40 cases of inherited neurological disorders with genetic diagnosis and/or pathological confirming. These disorders include cerebellar ataxia (SCA1, SCA2, SCA3, etc.), epileptic attacks related disorders (MELAS, MERRF, TSC, etc.), motor neuron related disorders (ALS, HSP, CMT, etc.), movement disorders (PD, PKD, DRD, etc.), ion channel diseases (hypokalemic periodic paralysis, normal potassium periodic paralysis), muscle diseases (DMD, FSHD, LSM, etc.), and dementia and psychiatric disorders (HD, CADASIL, CARASIL, etc.). With the format of case study, one type of diseases is discussed on each ch...
The Oxford Handbook of Nonsuicidal Self-Injury is a compendium of up-to-date research and knowledge of topics germane to the field of nonsuicidal self-injury (NSSI). Edited by renowned scholars Elizabeth E. Lloyd-Richardson, Imke Baetens, and Janis L. Whitlock, the handbook brings together cutting-edge research from a group of internationally distinguished scholars. It covers a wide array of topics including epidemiology, function, neurophysiological processes, lived experience, and intervention and prevention approaches. This comprehensive text will serve as a go-to guide for scholars, clinicians, and anyone with interest in understanding, treating, and preventing self-injury.