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Emerging Challenges of Cardiovascular and Metabolic Dysfunctions in Cardio-oncology: From Bench to Bedside
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Bioactive Natural Products
Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transfo...
Hf2cancer: Exploring bidirectional interaction between cardiovascular diseases and cancer
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Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues
This volume contains 17 short review articles classified into 3 parts. Part I consists of 7 articles dealing with basic aspects of contractile mechanism in skeletal and smooth muscle cells and also function of melanocytes having many properties common to those of smooth muscles. Part II and Part III contain articles dealing with pathological aspects of cardiac and smooth muscle cell functions, and dealing with factors influencing structure and function of cardiac and smooth muscle cells and tissues. The Editor believes that these articles are stimulating and informative for readers interested in basic, pathological and clinical aspects of muscle cells and tissues.
Monitoring endogenous GPCRs: lessons for drug design
G protein-coupled receptors (GPCRs) are integral membrane proteins forming the fourth largest superfamily in the human genome. Many of these receptors play key physiological roles and several pathologies have been associated with receptor functional abnormalities. GPCRs therefore represent important goals for drug design in pharmaceutical companies since they constitute the target of about one third of the drugs currently on the market. However, endogenous GPCRs are most often difficult to study because of a lack of tools to target them specifically and single out their response to physiological or drug-elicited stimulations. Hence, studies mostly focused on recombinant receptors expressed i...
The Microdosing Guidebook
Learn about the history, research, and helpful effects of microdosing psychedelic medicines like psilocybin, LSD, ecstasy, and more with this combination manual and workbook. Microdosing, or taking between 1/10th and 1/20th of the normal dose of a psychedelic drug is the latest way to improve performance, stave off chronic pain, and alleviate a variety of other ailments like anxiety and depression. Unlike a psychedelic trip, microdosing does not alter your mental status or interfere with day-to-day life. Part handbook and part workbook, The Microdosing Guidebook is your ultimate reference for safely using psychedelic medicine. Inside you’ll find: The most up-to-date research on psychedelics A complete history of psychedelics and their medicinal uses How to find the correct dose for your unique body and situation A place to track your experiences and improvements And much more! Whether you have experience with psychedelics or are simply curious to learn more, The Microdosing Guidebook has everything you need to get started on your healing journey.
G Protein-Coupled Receptor Kinases (GRKs) and Beta-Arrestins: New Insights into Disease Regulators
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Characterization and Regulation of Muscarinic Acetylcholine Receptor Signaling by Calmodulin
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