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Understanding Innovation Through Exaptation
This book explores the role of exaptation in diverse areas of life, with examples ranging from biology to economics, social sciences and architecture. The concept of exaptation, introduced in evolutionary biology by Gould and Vrba in 1982, describes the possibility that already existing traits can be exploited for new purposes throughout the evolutionary process. Edited by three active scholars in the fields of biology, physics and economics, the book presents an interdisciplinary collection of expert viewpoints illustrating the importance of exaptation for interpreting current reality in various fields of investigation. Using the lenses of exaptation, the contributing authors show how to vi...
Principles of Stem Cell Biology and Cancer
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem C...
Network physiology, insights in systems interactions and organ networks: 2021
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Frontiers in Anti-Cancer Drug Discovery, Volume (1)
"Frontiers in Anti-Cancer Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug di
In vitro and in vivo development of a topical drug for the treatment of equine skin cancer – based on naturally occurring and synthetically modified substances in plane bark
Equine sarcoids (ES) and equine malignant melanoma (EMM) are among the tumors affecting horses diagnosed most frequently. Both cutaneous neoplasms can be a significant cause of economic losses, morbidity and mortality in the animals. The treatment of equine skin cancer can be challenging and established, evidence-based therapies resulting in sustained tumor regression are rare. The pentacyclic, lupane-type triterpenes betulinic acid (BA) and betulin can be isolated from many botanical sources, predominantly from the bark of white birch and plane trees. In addition to various biological properties, they have gained attention mainly due to their anticancer features. Within the framework of the...
High-Risk Cutaneous Squamous Cell Carcinoma
This book is a cutting-edge resource that provides clinicians with the up-to-date practical knowledge required in order to manage SCC patients optimally. It summarizes newly available information relating to the definition of high-risk SCC, its pathophysiologic underpinnings, and its management. New prognostic information and staging systems are summarized that enable high-risk tumors to be defined more precisely than ever before. Many helpful tips are provided on the practical management of challenging cases, including multiple tumors/field cancerization, high-risk tumors, nodal metastases, and unresectable disease. The authors are all acknowledged experts in the emerging field of high-risk and advanced SCC.
Environmental Alteration Leads to Human Disease
This book aims to explore the impact of human alterations of Earth’s ecological systems on human health. Human activities are producing fundamental biophysical changes faster than ever before in the history of our species, which are accompanied by dangerous health effects. Drawing on advanced ecological principles, the book demonstrates the importance of using systemic medicine to study the effects of ecological alterations on human health. Planetary Health is an interdisciplinary field, but first of all it must be systemic and it needs a preferential relationship between Ecology and Medicine. This relation is to be upgrading, because today both ecology and medicine pursue few systemic cha...
Cancer Stem Cells
Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.
Programmable Matter
What Is Programmable Matter Programmable matter is matter which has the ability to change its physical properties in a programmable fashion, based upon user input or autonomous sensing. Programmable matter is thus linked to the concept of a material which inherently has the ability to perform information processing. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Programmable matter Chapter 2: Metamaterial Chapter 3: Electropermanent magnet Chapter 4: Self-reconfiguring modular robot Chapter 5: Claytronics Chapter 6: Cellular automaton Chapter 7: Quantum well Chapter 8: Synthetic biology (II) Answering the public top questions about programmable matter. (III) Real world examples for the usage of programmable matter in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of programmable matter' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of programmable matter.
