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Principles of Nanomedicine
The scope of nanotechnology in medical applications has expanded fast in the last two decades. With their unprecedented material properties, nanoscale materials present with unorthodox opportunities in a wide range of domains, including drug delivery and medical imaging. This book assembles the various facets of nanomedicine while discussing key issues such as physicochemical properties that enhance the appeal of nanomedicine. The book is an excellent resource for physicians, PhDs, and postdocs involved in nanomedicine research to learn and understand the scope and complexity of the subject. It begins with a short history of nanotechnology, followed by a discussion on the fundamental concepts and extraordinary properties of nanoscale materials, and then slowly unfolds into multiple chapters illustrating the uses of various nanomaterials in drug delivery, sensing, and imaging.
Handbook of Materials for Nanomedicine
The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.
HER2
This book exemplifies the evolution of oncogene HER2-encoded enzyme from its discovery to the stage of a fully recognized target for breast cancer therapy. Intensive research over the last three decades has uncovered major mechanisms that regulate the transformation of a normal tissue to a malignant tumor. However, to the disappointment of many molecular biologists, these significant advances in identifying oncogenes, tumor-suppressors and critical signalling pathways have generated only limited impact in clinical oncology. This frustration may not persist for long: tailor-made drugs developed specifically to recognize molecular targets, and intercept biochemical engines whose intricacy is well understood, are on the verge of revolutionizing contemporary medicine.
Operation Barbarossa: the Complete Organisational and Statistical Analysis, and Military Simulation Volume IIA
Operation Barbarossa: Volume IIA concerns the Wehrmacht. All the significant German weapon systems and combat squads used in the campaign are analysed using the quantitative methodology detailed in Volume I, along with the contextual history. An assessment of each weapon system's inherent 'combat power' is provided, as well as attributes such as the relative anti-tank, anti-personnel and anti-aircraft values. Volume IIA then focuses on the detailed Kriegstarkenachweisungen (KStN, or TOE) for German land units (including those in the West), as well as the unit's actual organisation and equipment. All significant units in the German Army (Heer), Waffen SS, Luftwaffe and security forces are included; ranging from the largest panzer divisions, down to small anti-aircraft companies, military-police units, Landesschutzen battalions, and rail-road and construction companies. In all cases the data is presented in detailed tables, using the weapon systems and combat squads previously analysed.
Drug Delivery
In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.
Automotive Literature Index
Vol. for 1947-76 indexes: Car and driver, Motor trend, and Road & track; 1977-81 indexes 15 American automotive journals.
