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We normally think of viruses in terms of the devastating diseases they cause, from smallpox to AIDS. But in The Life of a Virus, Angela N. H. Creager introduces us to a plant virus that has taught us much of what we know about all viruses, including the lethal ones, and that also played a crucial role in the development of molecular biology. Focusing on the tobacco mosaic virus (TMV) research conducted in Nobel laureate Wendell Stanley's lab, Creager argues that TMV served as a model system for virology and molecular biology, much as the fruit fly and laboratory mouse have for genetics and cancer research. She examines how the experimental techniques and instruments Stanley and his colleagues developed for studying TMV were generalized not just to other labs working on TMV, but also to research on other diseases such as poliomyelitis and influenza and to studies of genes and cell organelles. The great success of research on TMV also helped justify increased spending on biomedical research in the postwar years (partly through the National Foundation for Infantile Paralysis's March of Dimes)—a funding priority that has continued to this day.
“Delightful, delicious and so engaging . . . a mystery that keeps you coming back for more” from the author of Class Reunions Are Murder (Bibliophile Reviews). When her sleepwalking aunt is accused of committing murder, Poppy McAllister finds out there’s no rest for the weary . . . Between trying to get her gluten-free baking business off the ground and helping her aunt remodel her old Victorian into the Butterfly House Bed and Breakfast in Cape May, New Jersey, Poppy is ready to call, “Mayday!” And now Aunt Ginny—who’s a handful wide-awake—is sleepwalking on her new sleeping pill prescription and helping herself to neighbors’ snacks and knickknacks. Even more alarming, a l...
This book describes recent collaborations combining the expertise of applied mathematicians, engineers and geophysicists within a research training group (RTG) on "Modeling, Simulation and Optimization of Fluid Dynamic Applications”, funded by the Deutsche Forschungsgemeinschaft (DFG). The focus is on mathematical modeling, adaptive discretization, approximation strategies and shape optimization with PDEs. The balanced research program is based on the guiding principle that mathematics drives applications and is inspired by applications. With this leitmotif the RTG advances research in Modeling, Simulation and Optimization by an interdisciplinary approach, i.e., to stimulate fundamental ed...
This volume in honour of Jan N. Bremmer contains the contributions of numerous students, colleagues, and friends offered to him on the occasion of his 65th birthday. Throughout his career, Bremmer has distinguished himself as an internationally renowned scholar of religion both past and present, including first and foremost Greek and Roman religion, but also early Christianity and post-classical developments in religion and spirituality. In line with these three main areas of Bremmer’s research, the volume is divided into three parts, bringing together contributions from distinguished scholars in many fields. The result is a diverse book which provides a broad spectrum of original ideas and innovative approaches in the history of religions, thus reflecting the nature of the scholarship of Bremmer himself.
Rethinking Thought takes readers into the minds of 30 creative thinkers to show how greatly the experience of thought can vary. It is dedicated to anyone who has ever been told, "You're not thinking!", because his or her way of thinking differs so much from a spouse's, employer's, or teacher's. The book focuses on individual experiences with visual mental images and verbal language that are used in planning, problem-solving, reflecting, remembering, and forging new ideas. It approaches the question of what thinking is by analyzing variations in the way thinking feels. Written by neuroscientist-turned-literary scholar Laura Otis, Rethinking Thought juxtaposes creative thinkers' insights with ...
Ulrike Draesner is a prize-winning writer of novels, short stories, critical essays and poetry, and one of the foremost authors in Germany today. While a number of volumes have been published in German on her work, the current Companion offers the first volume on Draesner in English, capitalising on the interest in her work in Germany and further afield. Introducing Draesner’s major novels and short stories, poetry collections and essays, as well as giving an overview of existing research focusing on migration, memory, science, gender and bodily experience, chapters by international scholars in this volume also break new ground by focussing on visual culture, poetology, nature, the posthuman and Draesner’s reception of English literature and medieval culture. A comprehensive bibliography, commissioned interview and original writing by Draesner make the volume a valuable research tool for scholars and students. This will become essential reading for all those interested in Draesner, women’s writing, literature and history, and contemporary German prose and poetry.
This dissertation examines the impact of the type of referring expression on the acquisition of word order variation in German-speaking preschoolers. A puzzle in the area of language acquisition concerns the production-comprehension asymmetry for non-canonical sentences like "Den Affen fängt die Kuh." (“The monkey, the cow chases.”), that is, preschoolers usually have difficulties in accurately understanding non-canonical sentences approximately until age six (e.g., Dittmar et al., 2008) although they produce non-canonical sentences already around age three (e.g., Poeppel & Wexler, 1993; Weissenborn, 1990). This dissertation investigated the production and comprehension of non-canonical...
By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. Telling this history in full for the first time, Soraya de Chad...
In the early twentieth century, the eugenics movement won many supporters with its promise that social ills such as venereal disease, alcoholism, and so-called feeble-mindedness, along with many other conditions, could be eliminated by selective human breeding and other measures. The provinces of Alberta and British Columbia passed legislation requiring that certain “unfit” individuals undergo reproductive sterilization. Ontario, being home to many leading proponents of eugenics, came close to doing the same. In the Public Good examines three legal processes that were used to advance eugenic ideas in Ontario between 1910 and 1938: legislative bills, provincial royal commissions, and the ...
In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycl...