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Angiotensin and Blood Pressure Regulation examines the role of angiotensin in blood pressure regulation, with emphasis on its ability to influence the inotropic state directly via activation of myocardial receptors and indirectly by potentiating the release of catecholamines from sympathetic nerve terminals. The book also explains how angiotensin acts directly to regulate thirst and sodium appetite, and via antidiuretic hormone to control water reabsorption in the kidney. This book is comprised of eight chapters and begins with a review of the neuronal actions of angiotensin, primarily those in the brain, as well as the location and function of brain angiotensin II receptors. The effects of ...
Contains eleven contributions which address specific examples of the way in which animal experimentation leads to data applicable to human disease. Includes coverage of the ethics of animal use and advantages of animal models over alternate systems, including computer simulation, tissue culture, and in vitro biochemistry. Annotation copyrighted by Book News, Inc., Portland, OR
Recent Progress in Hormone Research, Volume 32 covers the proceedings of the 1975 Laurentian Hormone Conference. The book discusses genetic approaches to steroid hormone action; the cytochemical bioassay of hormones; and crystal structure of steroids. The text also describes the gonadotropin-releasing hormone and thyrotropin-releasing hormone; the ontogenesis of pituitary hormones and hypothalamic factors in the human fetus; and the etiologies of sexual maturation. The epidemiologic studies of diabetes in the Pima Indians; and the adrenal cortex and essential hypertension are also considered. The book further tackles the testicular control of follicle-stimulating hormone secretion; and nuclear receptors and the initiation of thyroid hormone action. The text then encompasses the receptor function and ion transport in turkey erythrocytes; the regulation of adenylate cyclase coupled beta-adrenergic receptors; and the control of cyclic AMP metabolism in parental and hybrid somatic cells. The molecular mechanisms of cyclic AMP action are also looked into. Endocrinologists, physiologists, molecular biologists, and biochemists will find the book invaluable.
Some of the leading scientists in the field of hypertension accepted an invi tation to actively participate in an international symposium on primary hypertension. Scientists from 13 countries - from western, southern, and eastern Europe, Australia, and the United States - were present. The meeting was held in Cologne in March 1985. After previous meetings and workshops at Titisee in the Black Forest and several symposia on the renin angiotensin-aldosterone system here in Cologne, this symposium on prima ry hypertension was organized in order to induce and to stimulate critical discussion on the basic pathogenetic mechanisms involved and the recently established therapeutic implications. Nume...
The renin-angiotensin system and the mechanisms regulating this system developed during the adaptive evolution of verte brates, along with many other systems involved in the in tegrated survival of the organism. Because animal species have evolved from common ancestral populations, a basis for the comparison of body structures and physiological processes ex ists among animal groups belonging to different classifications. The comparative approach provides a better understanding of the structure and function of adaptive systems and facilitates the development of general principles governing these systems among animal groups; further, this approach reveals significant characteristics specific t...
This text presents the final reports of the 17 research groups supervised by the CEC programme COMAC-BIOLOGY, relating applications such as: standardization of diagnostic procedures; application of new biological techniques to health problems; sharing of technologies and reagents; provision of special biological systems; evaluation of effectiveness of measures aiming at health care; and collection, storage and dissemination of information.
The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.
reached full definition in the 1940s by Kempner diet. The important role of adrenal aldosterone and associates in demonstrating the beneficial ef secretion in supporting human hypertension is now fects of a low salt rice diet for treating hypertensive well recognized as are the beneficial effects of patients. It became apparent that the value of rice blockade, especially in low-renin patients who ex was wholly related to its sodium content. A rice hibit inappropriate or absolute excesses of aldoste diet, or any other stringent low sodium diet, rone secretion. Further definition of the more sub greatly improves or completely corrects the hyper tle participation of aldosterone and of the facto...