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Many of the systemic autoimmune diseases seen in children are different from those seen in adults making them a special problem for physicians and scientists who care for the affected children and study their diseases. Benefiting both pediatric and adult rheumatologists, as well as physicians from other specialties, this volume covers the latest advances in pathogenesis and clinical management of common conditions seen in pediatric rheumatology practices.
Ophthalmic researchers and clinicians alike increasingly are recognizing the importance of the vitreous body in the physiology, biochemistry, and pathology of the inner eye. The Vitreous and Vitreoretinal Interface, with contributions by vitreoretinal surgeons and laboratory eye researchers, presents the most up-to-date clinically relevant data. This book provides evidence of the vitreous body's significant role in preserving retinal homeostasis, as well as the close connection between vitreous traction and such conditions as retinal inflammation, retinal vascular occlusions, macular edema, proliferative diabetic retinopathy, and giant retinal tears. The particular vitreal changes that occur in aphakia, myopia, retinitis pigmentosa, and idiopathic giant retinal breaks, as well as recent advances in open-sky vitreous surgery and in the search for useful vitreous substitutes are discussed.
also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have co...
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screen...
The Apostle Paul's reference to the tongues of angels (1 Cor 13.1) has always aroused curiosity, but it has rarely been the object of a history-of-traditions investigation. Few readers of Paul's words are aware of the numerous references and allusions to angelic languages in Jewish and Christian texts. John C. Poirier presents the first full-length study of the concept of angelic languages, and the most exhaustive attempt to assemble the evidence for that concept in ancient Jewish and early Christian texts. He discusses possible references to angelic languages in the New Testament, pseudepigraphic writings (both Jewish and Christian), the Dead Sea scrolls, rabbinic texts, patristic references, magical writings, and epigraphy. The discussion is divided between those witnesses that understand angels to speak Hebrew, and those that understand angels to speak an esoteric heavenly language.
The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how the vitreous is composed and what role it plays in normal physiology. Over the years, however, many studies have produced independent findings concerning vitreous biochemistry, structure, and physiology. The Vitreous organizes these findings into a well-constructed compendium that not only addresses the most current scientific knowledge, but also reviews historical perspec tives in a manner that lends richness to the scope of the book. The first few chapters present an exhaustive, yet readable, ...
Dr. Noakes explores the physiology of running, all aspects of training, and recognizing, avoiding, and treating injuries. 133 illustrations.
This addition to the Handbook series will allow the tennis coach, athlete, and medical professional responsible for their care to improve technique, training and performance, and to reduce the risk of injury. When injury does occur, Tennis will aid quick accurate diagnosis and treatment, and effective rehabilitation so that the tennis player can return to peak performance with the minimum of fuss.