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Discrete probability theory and the theory of algorithms have become close partners over the last ten years, though the roots of this partnership go back much longer. The papers in this volume address the latest developments in this active field. They are from the IMA Workshops "Probability and Algorithms" and "The Finite Markov Chain Renaissance." They represent the current thinking of many of the world's leading experts in the field. Researchers and graduate students in probability, computer science, combinatorics, and optimization theory will all be interested in this collection of articles. The techniques developed and surveyed in this volume are still undergoing rapid development, and many of the articles of the collection offer an expositionally pleasant entree into a research area of growing importance.
The articles in this volume present the state of the art in a variety of areas of discrete probability, including random walks on finite and infinite graphs, random trees, renewal sequences, Stein's method for normal approximation and Kohonen-type self-organizing maps. This volume also focuses on discrete probability and its connections with the theory of algorithms. Classical topics in discrete mathematics are represented as are expositions that condense and make readable some recent work on Markov chains, potential theory and the second moment method. This volume is suitable for mathematicians and students.
Praised by Entertainment Weekly as “the man who put the fizz into physics,” Dr. Len Fisher turns his attention to the science of cooperation in his lively and thought-provoking book. Fisher shows how the modern science of game theory has helped biologists to understand the evolution of cooperation in nature, and investigates how we might apply those lessons to our own society. In a series of experiments that take him from the polite confines of an English dinner party to crowded supermarkets, congested Indian roads, and the wilds of outback Australia, not to mention baseball strategies and the intricacies of quantum mechanics, Fisher sheds light on the problem of global cooperation. The outcomes are sometimes hilarious, sometimes alarming, but always revealing. A witty romp through a serious science, Rock, Paper, Scissors will both teach and delight anyone interested in what it what it takes to get people to work together.
Focusing on the work of Sir John Kingman, one of the world's leading researchers in probability and mathematical genetics, this book touches on the important areas of these subjects in the last 50 years. Leading authorities give a unique insight into a wide range of currently topical problems. Papers in probability concentrate on combinatorial and structural aspects, in particular exchangeability and regeneration. The Kingman coalescent links probability with mathematical genetics and is fundamental to the study of the latter. This has implications across the whole of genomic modeling including the Human Genome Project. Other papers in mathematical population genetics range from statistical aspects including heterogeneous clustering, to the assessment of molecular variability in cancer genomes. Further papers in statistics are concerned with empirical deconvolution, perfect simulation, and wavelets. This book will be warmly received by established experts as well as their students and others interested in the content.
No leading university department of mathematics or statistics, or library, can afford to be without this unique text. Leading authorities give a unique insight into a wide range of currently topical problems, from the mathematics of road networks to the genomics of cancer.
The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its appl...
Genetic algorithms are founded upon the principle of evolution, i.e., survival of the fittest. Hence evolution programming techniques, based on genetic algorithms, are applicable to many hard optimization problems, such as optimization of functions with linear and nonlinear constraints, the traveling salesman problem, and problems of scheduling, partitioning, and control. The importance of these techniques is still growing, since evolution programs are parallel in nature, and parallelism is one of the most promising directions in computer science. The book is self-contained and the only prerequisite is basic undergraduate mathematics. This third edition has been substantially revised and extended by three new chapters and by additional appendices containing working material to cover recent developments and a change in the perception of evolutionary computation.
Most probability problems involve random variables indexed by space and/or time. These problems almost always have a version in which space and/or time are taken to be discrete. This volume deals with areas in which the discrete version is more natural than the continuous one, perhaps even the only one than can be formulated without complicated constructions and machinery. The 5 papers of this volume discuss problems in which there has been significant progress in the last few years; they are motivated by, or have been developed in parallel with, statistical physics. They include questions about asymptotic shape for stochastic growth models and for random clusters; existence, location and properties of phase transitions; speed of convergence to equilibrium in Markov chains, and in particular for Markov chains based on models with a phase transition; cut-off phenomena for random walks. The articles can be read independently of each other. Their unifying theme is that of models built on discrete spaces or graphs. Such models are often easy to formulate. Correspondingly, the book requires comparatively little previous knowledge of the machinery of probability.
Communication is a critical yet often overlooked part of data science. Communicating with Data aims to help students and researchers write about their insights in a way that is both compelling and faithful to the data. General advice on science writing is also provided, including how to distill findings into a story and organize and revise the story, and how to write clearly, concisely, and precisely. This is an excellent resource for students who want to learn how to write about scientific findings, and for instructors who are teaching a science course in communication or a course with a writing component. Communicating with Data consists of five parts. Part I helps the novice learn to writ...
This volume contains the proceedings of the Workshop on Monte Carlo Methods held at The Fields Institute for Research in Mathematical Sciences (Toronto, 1998). The workshop brought together researchers in physics, statistics, and probability. The papers in this volume - of the invited speakers and contributors to the poster session - represent the interdisciplinary emphasis of the conference. Monte Carlo methods have been used intensively in many branches of scientific inquiry. Markov chain methods have been at the forefront of much of this work, serving as the basis of many numerical studies in statistical physics and related areas since the Metropolis algorithm was introduced in 1953. Stat...