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Examines the disease that is becoming America's fastest-growing epidemic, revealing the author's own bout with Type 1 diabetes, the science behind the disease, and the social and economic impact of diabetes in the United States.
Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.
The Encyclopedia includes 125 entries, beginning with the origins of genetics including historical background on the work of Gregor Mendel and Charles Darwin, and progressing to the structure of DNA and modern theories such as selfish genes. All branches of genetics are covered, including the genetics of bacteria, viruses, insects, animals and plants, as well as humans. Important topical issues such as the human genome project, bioethics, the law and genetics, genetic disorders, GM crops, and the use of transgenic animals for food and pharmaceutical products are fully surveyed. A section on techniques and biotechnology includes modern methods of analysis, from DNA fingerprinting to the new s...
The Arctic can be viewed as an integrated system, characterised by intimate couplings between its atmosphere, ocean and land, linked in turn to the larger global system. This comprehensive, up-to-date assessment begins with an outline of early Arctic exploration and the growth of modern research. Using an integrated systems approach, subsequent chapters examine the atmospheric heat budget and circulation, the surface energy budget, the hydrologic cycle and interactions between the ocean, atmosphere and sea ice cover. Reviews of recent directions in numerical modelling and the characteristics of past Arctic climates set the stage for detailed discussion of recent climate variability and trends, and projected future states. Throughout, satellite remote sensing data and results from recent major field programs are used to illustrate key processes. The Arctic Climate System provides a comprehensive and accessible overview of the subject for researchers and advanced students in a wide range of disciplines.