Seems you have not registered as a member of localhost.saystem.shop!
You may have to register before you can download all our books and magazines, click the sign up button below to create a free account.
Our Trespasses
An anonymous letter, seemingly from an old lady, arrives at a South London Police Station. It contains the confession to the murder of a vagrant, found dead at an underground train station.The story began some forty-five years earlier in 1966 London, a time of cultural and sexual liberation - for some. For two teenage sisters, Midge and Bridie Dolan, growing up in the Catholic community, the revolution couldn't be further than if it was happening on Mars. All the two Motown-mad girls want to do is go to the nightclub The Palais Royale, and if their wayward cousin Jimmy can escort them there and back, it looks like they'll get their wish.Unaware this particular Friday outing is going to irrevocably change their lives forever, the sisters have high hopes of what the night will bring - yet fate has other plans.A page-turning drama set in 1960's London, a time as harsh and uncompromising as it ever was for those trying to navigate the right path through tumultuous times.
Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response
Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response provides the most comprehensive body of knowledge available on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients. As a consequence of the intrinsic chromosomal and genetic instability of the tumor genome, it is generally believed that tailoring of chemotherapy in cancer - tients might be achieved by molecular analysis of patient tumor DNA. In addition, to reduce the toxicity risk of patients, the tumor DNA information should be in- grated with the available data on polymorphic drug-metabolizing enzyme and tra- porter genes mediating the exposure of patients...
Official Gazette of the United States Patent and Trademark Office
description not available right now.
DNA Repair in Cancer Therapy
A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.
Socio-economics of Personalized Medicine in Asia
The second decade of the twenty-first century has witnessed a surging interest in personalized medicine with the concomitant promise to enable more precise diagnosis and treatment of disease and illness, based upon an individual’s unique genetic makeup. In this book, my goal is to contribute to a growing body of literature on personalized medicine by tracing and analyzing how this field has blossomed in Asia. In so doing, I aim to illustrate how various social and economic forces shape the co-production of science and social order in global contexts. This book shows that there are inextricable transnational linkages between developing and developed countries and also provides a theoretically guided and empirically grounded understanding of the formation and usage of particular racial and ethnic human taxonomies in local, national and transnational settings. The Open Access version of this book, available at http://www.taylorfrancis.com/doi/view/10.4324/9781315537177 has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
Principles of Pharmacogenetics and Pharmacogenomics
This textbook presents the latest information on pharmacogenetics and pharmacogenomics for students, professionals and researchers.
