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This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.
This book contains accepted papers presented at SOCO 2022 conference held in the beautiful and historic city of Salamanca (Spain), in September 2022. Soft computing represents a collection or set of computational techniques in machine learning, computer science, and some engineering disciplines, which investigate, simulate, and analyze very complex issues and phenomena. After a thorough peer-review process, the 17th SOCO 2022 International Program Committee selected 64 papers which are published in these conference proceedings and represent an acceptance rate of 60%. In this relevant edition, a particular emphasis was put on the organization of special sessions. Seven special sessions were o...
This book of Lecture Notes in Networks and Systems contains accepted papers presented at the 15th International Conference on Computational Intelligence in Security for Information Systems (CISIS 2022) and the 13th International Conference on EUropean Transnational Education (ICEUTE 2022). These conferences were held in the beautiful city of Salamanca, Spain, in September 2022. The aim of the CISIS 2022 conference is to offer a meeting opportunity for academic and industry-related researchers belonging to the various, vast communities of computational intelligence, information security, and data mining. The need for intelligent, flexible behaviour by large, complex systems, especially in mis...
This book of Advances in Intelligent and Soft Computing contains accepted papers presented at SOCO 2021 conference held in the beautiful and historic city of Bilbao (Spain), in September 2021. Soft computing represents a collection or set of computational techniques in machine learning, computer science, and some engineering disciplines, which investigate, simulate, and analyze very complex issues and phenomena. After a through peer-review process, the 16th SOCO 2021 International Program Committee selected 78 papers which are published in these conference proceedings and represents an acceptance rate of 48%. In this relevant edition, a special emphasis is put on the organization of special ...
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This book contains accepted papers presented at SOCO 2020 conference held in the beautiful and historic city of Burgos (Spain), in September 2020. Soft computing represents a collection or set of computational techniques in machine learning, computer science and some engineering disciplines, which investigate, simulate, and analyze very complex issues and phenomena. After a through peer-review process, the SOCO 2020 International Program Committee selected 83 papers which are published in these conference proceedings and represents an acceptance rate of 35%. Due to the COVID-19 outbreak, the SOCO 2020 edition was blended, combining on-site and on-line participation. In this relevant edition ...
This book constitutes the refereed proceedings of the 17th International Conference on Hybrid Artificial Intelligent Systems, HAIS 2022, held in Salamanca, Spain, in September 2022. The 43 full papers presented in this book were carefully reviewed and selected from 67 submissions. They were organized in topical sections as follows: bioinformatics; data mining and decision support systems; deep learning; evolutionary computation; HAIS applications; image and speech signal processing; and optimization techniques.
The early 1960s are remembered for the emergence of new radical movements influenced by the Cuban Revolution. One such protest movement rose in the Mexican state of Chihuahua. With large timber companies moving in on the forested sierra highlands, campesinos and rancheros did not sit by as their lands and livelihoods were threatened. Continuing a long history of agrarian movements and local traditions of armed self-defense, they organized and demanded agrarian rights. Thousands of students joined the campesino protests in long-distance marches, land invasions, and direct actions that transcended political parties and marked the participants’ emergence as political subjects. The Popular Gue...