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Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological re...
The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest.The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is wri...
Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerati...
This book provides a practical guide to experimental methods for studying the development of invertebrate deuterostomes, such as sea urchins, ascidians, hemichordates, and amphioxus. These model organisms are of contemporary and historical importance to the study of developmental biology, particularly genomic research. The chapters provide detailed experimental protocols that cover a broad range of topics in modern experimental methods. Topics covered range from rearing embryos to the care of adult animals, while also presenting the basic experimental methods including light and electron microscopy, used to study gene expression, transgenics, reverse genetics, and genomic approaches. * Covers a wide range of methods, from classical embryology through modern genomics * Discusses animals related to vertebrates, providing a valuable evolutionary perspective * Includes a practical guide to the use of sea urchins in the teaching laboratory
The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society. The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers,...
A daughter’s inspiring biography of her father, who lost his sight in a massive maritime disaster—and went on to build a rewarding life and career. Eric Davidson was a beautiful, fair-haired toddler when the historic Halifax Explosion struck, devastating the Nova Scotia capital and killing almost two thousand people while seriously injuring thousands more. Eric lost both eyes—a tragedy that his mother never fully recovered from. Eric, however, was positive and energetic. He also developed a fascination with cars and how they worked—and he later decided, against all likelihood, to become a mechanic. Assisted by his brothers, who read to him from manuals, he worked hard, passed examinations, and carved out a decades-long career. This is the true story of his remarkable life and relentless determination, as told by his daughter.
Pattern Formation in Morphogenesis is a rich source of interesting and challenging mathematical problems. The volume aims at showing how a combination of new discoveries in developmental biology and associated modelling and computational techniques has stimulated or may stimulate relevant advances in the field. Finally it aims at facilitating the process of unfolding a mutual recognition between Biologists and Mathematicians of their complementary skills, to the point where the resulting synergy generates new and novel discoveries. It offers an interdisciplinary interaction space between biologists from embryology, genetics and molecular biology who present their own work in the perspective of the advancement of their specific fields, and mathematicians who propose solutions based on the knowledge grasped from biologists.
When it comes to implementing successful ecological restoration projects, the social, political, economic, and cultural dimensions are often as important as-and sometimes more important than-technical or biophysical knowledge. Human Dimensions of Ecological Restoration takes an interdisciplinary look at the myriad human aspects of ecological restoration. In twenty-six chapters written by experts from around the world, it provides practical and theoretical information, analysis, models, and guidelines for optimizing human involvement in restoration projects. Six categories of social activities are examined: collaboration between land manager and stakeholders ecological economics volunteerism ...
This work examines rules, system properties and mechanisms underlying developmental gene regulation in a broad range of organisms. It covers the thoughts and theories, experimental inventions, strategies and successes of recent investigations into developmental processes in organisms ranging from yeast and fungi to higher eucaryotes. Some of the specific topics covered include: calcium, cell cycle control, the role of protein kinase
Moving between philosophy and history, Arnold Davidson elaborates a powerful new method for considering the history of concepts and the nature of scientific knowledge, a method he calls "historical epistemology." He applies this method to the history of sexuality.