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Key Players in Systemic Sclerosis: The Immune System and Beyond
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Inducible Lymphoid Organs
This book sheds new light on “inducible” lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under various pathogenic conditions. Accomplished immunologists demonstrate that the physiological role of these ILOs is completely different from that of central lymphoid organs, i.e., the lymph nodes or spleen. In addition to the central organs, the ILOs are considered essential structures for the efficient elicitation of adaptive immune responses in lesions. The respective chapters highlight examples from multiple sites, e.g. the skin, lung, intestinal tract, genital tract, the synovial membrane of the joints and artificial lymph nodes. Accordingly, readers will learn that ILO structure and function can vary substantially, depending on the context. Presenting the results of the latest immunological research, the book offers a fascinating and insightful read for both scientists and clinicians in the areas of infectious and immune-associated diseases.
Advance in B-cell therapies for the treatment of rheumatic and musculoskeletal diseases
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Sjögren’s Syndrome: Pathogenicity, Novel targets and Antigens.
Dr. Baer is the site PI for a clinical trial investigating treatments related to Sjogren’s Syndrome, in conjunction with Viela Bio. The other Topic Editors declare no competing interests with relation to the topic theme.
Rheumatology in Practice
Rheumatology in Practice offers chapters which are organised and built around anatomical and regional syndromes, so reinforcing the evidence-based approach. As readers progress through the text they are given more demanding and challenging questions, encouraging them to use their diagnostic skills to identify the main syndromes and the underlying diseases responsible for the disorders in question. The text is lavishly illustrated in full colour, with detailed photos of patient examinations, complemented by radiographs and full colour line illustrations. The text also benefits from the use of summaries using coloured boxing to identify key points in diagnosis and management. Written by two of the most respected clinicians in the discipline, this book will be essential reading for rheumatologists in practice and training.
Hydrogeology
HYDROGEOLOGY Hydrogeology: Principles and Practice provides a comprehensive introduction to the study of hydrogeology to enable the reader to appreciate the significance of groundwater in meeting current and future environmental and sustainable water resource challenges. This new edition has been thoroughly updated to reflect advances in the field since 2014 and includes over 350 new references. The book presents a systematic approach to understanding groundwater starting with new insights into the distribution of groundwater in the Earth’s upper continental crust and the role of groundwater as an agent of global material and elemental fluxes. Following chapters explain the fundamental phy...
