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Tissue-Specific Cell Signaling
Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
New Trends in Urban Drainage Modelling
This book addresses the latest research advances, innovations, and applications in the field of urban drainage and water management as presented by leading researchers, scientists and practitioners from around the world at the 11th International Conference on Urban Drainage Modelling (UDM), held in Palermo, Italy from 23 to 26 September, 2018. The conference was promoted and organized by the University of Palermo, Italy and the International Working Group on Data and Models, with the support of four of the world’s leading organizations in the water sector: the International Water Association (IWA), International Association for Hydro-Environment Engineering and Research (IAHR), Environment...
Assessing Health-related Quality of Life of Children
Assessing health-related quality of life (HRQOL) of Children has been a popular topic in recent years worldwide. However, there are several issues/gaps in this research area which need to be addressed. For instance, previous studies on HRQOL of Children populations have normally used HRQOL instruments designed for adults. These measurements may not be suitable for children as they are in a series of cognitive developmental stages and have different perspectives towards the relative importance of HRQOL dimensions. In order to tackle this issue and to accurately measure children’s HRQOL, a set of dedicated HRQOL instruments should be first developed and validated. The validated instruments could then be applied to the population measuring their HRQOL. In addition, the HRQOL information collected could be translated into health utility score if it is measured by utility instruments (e.g., EQ-5D-Y) for the population. Moreover, the relevant studies on these issues is still lacking especially in non-western countries.
Forensic Psychology of Spousal Violence
Exploring the dynamics between victim and offender is paramount to answering important issues of character and vital for forensic research. This involves examining the role of the victim during and after victimization; this process is especially important for spousal violence because of the interactive process between the victim and the offender.Forensic Psychology of Spousal Violence covers the phenomenon of spousal violence and its different forms, discussing the consequences of abuse, providing research tips to be used in the field, including relevant case studies and much more. The innovative approach of this text fills a void in the current understanding of spousal violence. - Uses international statistics to present data of women battered and/or deceased to educate, change mindsets and practices and ultimately reduce the number of battered women and spousal homicides in the future - Includes current case studies - Includes best practices for spousal abuse investigations - Portable for use in fieldwork
Why I Believe in God
João de Deus Brasil's book comprises two independent but related works: Why I Believe in God and Atheism: a Self-Delusion. In Why I Believe in God, the author reveals the origins of his faith whereas in Atheism: a Self-Delusion he refutes atheists' arguments expressed by their current world leader, Richard Dawkins, in his best-seller God, a Delusion. Regarding the renowned biologist's ideas, João de Deus states: - In his book, Richard Dawkins does not provide any theory capable of scientifically justifying his negation of God's existence. And besides, he does not put forward any evidence whatsoever, either scientific or empirical, in support of that nonexistence. - Between the lines of his...
Mulheres e política no Brasil
Com base na atuação política de 69 mulheres inseridas na vida pública brasileira, o livro busca pela contextualização dos desafios institucionais e culturais relativos à igualdade de gênero no Brasil, aponta para princípios de despertar político em contextos individuais e coletivos, de fomento à participação política e sobre o próprio funcionamento democrático local. A produção tem como objetivo, além de gerar novos dados sobre o recorte descrito, o desenvolvimento estratégico de ferramentas motivadoras para a projeção da vida política de mulheres em sua diversidade representativa, como instrumento de enfrentamento à baixa taxa participativa e aos custos participativo...
Major Companies of Europe 2003
This directory is part of a six-volume set that provides data on over 36,000 European companies. Covering Portugal, Spain, Sweden and Switzerland, it provides information such as: address, phone and fax numbers, e-mail and Web addresses, listings of a company's activities, parents, subsidiaries and agents, brands and trademarks and financial information for 2001 and 2002.
