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Lymphoma
A cutting-edge collection of readily reproducible molecular techniques to better understand, classify, and treat lymphoma. Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and to apply gene arrays to the question of biological heterogeneity in morphologically similar diseases. Research methodologies that are highly likely to become routine practice in the future, such as DNA microarray and immunoglobulin V-gene rearrangements, and measurement of minimal disease, are included. There are also molecular techniques for providing for producing novel therapeutics, such as a DNA vaccine with patient-specific sequences derived from the lymphoma in question.
Social Skills Training for Adolescents with General Moderate Learning Difficulties
A resource for educators offers an effective tool to help teenagers with learning difficulties develop skills in social interaction, communication and conflict resolution, and to build their confidence and self-esteem.
Chilly Milly Moo
Milly Moo wants only one thing - to churn out the finest, loveliest, tastiest, creamiest milk. But there's a problem - she's far too hot. Milly Moo dreams of a freezing cold land and, as the temperature drops, something very exciting happens...
Chromosome Analysis Protocols
Chromosomes, as the genetic vehicles, provide the basic material for a large proportion of genetic investigations, from the construction of gene maps and models of chromosome organization, to the inves tigation of gene function and dysfunction. The study of chromosomes has developed in parallel with other aspects of molecular genetics, beginning with the first preparations of chromosomes from animal cells, through the development of banding techniques, which permitted the unequivocal identification of each chromosome in a karyotype, to the present analytical methods of molecular cytogenetics. Although some of these techniques have been in use for many years, and can be learned relatively eas...
Raw Life, New Hope
The Cape Flats, a windswept, barren and sandy area which rings Cape Town, is home to more than a million people. Many live here in sprawling shack settlements. The post-apartheid state is attempting to eradicate such settlements by providing formal houses in planned residential estates. Raw Life, New Hope is a longitudinal study of the residents of one such shack settlement, The Park, who moved to new, 'formal' houses in The Village, at the turn of the millennium. It introduces readers to core social science topics and modes of theorising. Over 17 years the author has traced how ordinary people attempt to live in accord with their ideals of decency under almost impossible circumstances, and the effects of material changes in their lives after 1994, including the provision of housing. Photos, maps, anecdotes, recipes and philosophical reflections on subjects that arose during conversations elicit a sense of the everyday and of how people try to solve the problems of poverty
Monitoring Elder Compliance and Response
This is a field-tested open learning resource for self-study by the community nurse which can be used either on an entirely self-learning basis, or as a module in a course in community nursing. It's focus is on the challenge of improving and monitoring elder compliance with medication regimes.
Secrets Never To Be Told
'Secrets Never to be Told' is an extraordinary story, compellingly told, which unravels a century and a half of family secrets. It reveals how being born illegitimate shaped the lives of two women - one of them, the author. Starting with a letter revealing a mystery inheritance, the author goes on a five- year quest taking her from Victorian Cambridge to modern Vancouver. She uncovers how her cousin Jessie emigrated to Canada, one of thousands of female domestic servants exported as 'surplus' women before the First World War. Woven alongside the contemporary detective investigation on the trail of one immigrant's untold story, is that of the author's strange 1960s childhood of social isolation in a Midlands city, obsessed with a world seen through TV - and with the Beatles.
Hyde and Squeak
Would YOU dare to eat a beastly-looking jelly? Squeak the mouse just can't resist a taste . . . Slurp! Burp! Grunt! Growl! Uh-oh! Squeak has turned into Hyde – a massive, hungry monster mouse! Look out! Hyde and Squeak is a hilarious comic-book twist on the classic tale of Jekyll and Hyde. Created by author-illustrator Fiona Ross (Ballet Cat, Chilly Milly Moo), this wonderfully disgusting picture book will appeal to fans of The Dinosaur that Pooped the Bed.
