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Youth Unemployment and Joblessness
Youth unemployment and joblessness are major issues for national governments and international organizations across the globe. In this respect, the school-to-work transition challenge is increasingly raising the interest of companies, education and training institutions, families and young people themselves, who are often involved in precarious and illegal forms of employment, in many countries of the world. In the field of industrial and labour relations, the school-to-work perspective seems particularly suitable for policy formulation and assessment: the broad and complex range of tools, strategies and policies for enabling youth training and their access to the labour market is deserving of a closer analysis at an international level in a time when jobless recovery threatens national economies. The ADAPT LABOUR STUDIES BOOK-SERIES has in connection been set up with a view to achieving a better understanding of the causes, consequences and possible responses to the issue in a global dimension through an interdisciplinary and comparative approach.
Multiple Myeloma
This book deals with the diagnosis and treatment of multiple myeloma. Multiple myeloma is a plasma cell disorder, the prognosis of which has dramatically improved in the last years thanks to new immunomodulatory drugs, proteasome inhibitors, and monoclonal antibodies, in relapsed/refractory disease and a diagnosis. Chapters cover such topics as prognostic and predictive factors in newly diagnosed multiple myeloma, treatment approaches, antibody therapies, and three-dimensional (3D) models mimicking multiple myeloma bone marrow–microenvironment interactions.
Women in Cytokines and Soluble Mediators in Immunity
We are delighted to present the inaugural Frontiers in Immunology “Women in Cytokines and Soluble Mediators in Immunity” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and Science, Technology, Engineering and Mathematics (STEM) research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
mTOR in Human Diseases
The mechanistic target of rapamycin (mTOR) is a major signaling intermediary that coordinates favorable environmental conditions with cell growth. Indeed, as part of two functionally distinct protein complexes, named mTORC1 and mTORC2, mTOR regulates a variety of cellular processes, including protein, lipid, and nucleotide synthesis, as well as autophagy. Over the last two decades, major molecular advances have been made in mTOR signaling and have revealed the complexity of the events implicated in mTOR function and regulation. In parallel, the role of mTOR in diverse pathological conditions has also been identified, including in cancer, hamartoma, neurological, and metabolic diseases. Through a series of articles, this book focuses on the role played by mTOR in cellular processes, metabolism in particular, and highlights a panel of human diseases for which mTOR inhibition provides or might provide benefits. It also addresses future studies needed to further characterize the role of mTOR in selected disorders, which will help design novel therapeutic approaches. It is therefore intended for everyone who has an interest in mTOR biology and its application in human pathologies.
Italians of Northeastern Pennsylvania
Pictorial history of the Italian community of northeastern Pennsylvania, one of the region's largest and most visible ethnic groups; covers the immigration experience and offers a glimpse into the lives of today's Italian-Americans of northeastern Pennsylvania.
Il testo unico dell'apprendistato e le nuove regole sui tirocini
Analisi del Testo uico sulla disciplina dell'apprendistato, valevole sia per il settore privato che pubblico. Normativa sui tirocini formativi e di orientamento.
Per il lavoro
«È proprio nell'incontro-scontro tra la dimensione soggettiva e antropologica del lavoro e quello che possiamo indicare come ‘il principio di realtà' che si decide, in larga misura, il successo o l'insuccesso dell'Italia nel far fronte alla sfida posta dai mutamenti del contesto mondiale». Camillo RuiniUn profondo malessere affligge in Italia il mondo del lavoro; un malessere reso più drammatico dalla grave crisi economica in corso. I tratti di questo malessere sono molteplici e presentano in genere una maggiore gravità al Sud che al Centro e al Nord del paese. I motivi sono la scarsità endemica di lavoro, che colpisce soprattutto le generazioni più giovani e le donne; la mancanza ...
Città e guerra : difese, distruzioni, permanenze delle memorie e dell’immagine urbana. Tomo II : tracce e patrimoni
[Italiano]: In un momento così significativo per la storia europea e mondiale, questo volume vuole essere la raccolta di riflessioni scientifiche condotte sui rapporti tra le scelte politiche, le azioni militari e la fisionomia delle città e del paesaggio urbano, sull’evoluzione delle strutture e delle tecniche di difesa, sulla rappresentazione della guerra e dei suoi effetti sull’immagine urbana, sul recupero delle tracce della memoria cittadina. Da una parte il campo delle Digital Humanities apre nuove prospettive per studiare l'immagine della città prima, durante e dopo la guerra, dall’altro le tecnologie digitali impegnano studiosi e ricercatori di varie discipline: in particola...
