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Mitochondria are critical to the survival of cells, therefore, it is not surprising that abnormalities in mitochondrial function may lead to human disease. This book concentrates on the biology and pathology of mitochondria, covering some ot the important basic science features of the biology of mitochondria. It then moves on to discuss the breadth of human diseases related to mitochondrial dysfunction, including Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Alzheimer's disease.* Provides comprehensive coverage of basic science and clinical features of mitochondrial dysfunction* Presents detailed analysis of "hot" topics in mitochondrial function and neurodegenerative diseases* Includes outstanding list of contributing authors
Craniosynostosis - the premature fusion of the cranial sutures of an infant’s skull - is a challenging and complex condition that can occur as part of a syndrome or in isolation. In the last two decades increased knowledge about the structure and function of the human genome has enabled the discovery of the molecular etiologies of most forms of syndromic craniosynostosis, which in turn has allowed for the analysis of normal and abnormal sutural biology from the atomic to the population-based level. In parallel with the increase in basic biological understanding, advances in clinical diagnosis and treatment have been achieved including improved prenatal imaging technology and craniofacial s...
This issue of Surgical Clinics of North America focuses on Robotic Surgery, and is edited by Dr. Julio Teixeira. Articles will include: History of Computer-assisted Surgery; Robotic Cardiac Surgery; Robotic Thoracic Surgery; Robotic Foregut Surgery; Robotic Liver Resection; Robotic Cholecystectomy; Robotic Pancreatic and Solid Surgery; Robotic Colorectal Surgery; Robotic Urology Surgery; Robotic Vental Hernia Surgery; Robotic Inguinal Hernia Surgery; Robotic Bariatric Surgery; Robotic Pediatric Surgery; Robotic Gynecological Surgery; Complications of Robotic Surgery; and more!
Sarcoma: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Sarcoma: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Sarcoma: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Critical Care of Children with Heart Disease will summarize the comprehensive medical and surgical management of the acutely-ill patient with congenital and acquired cardiac disease. The aim of the book is to teach bedside physicians, nurses and other caregivers, basic and practical concepts of anatomy, pathophysiology, surgical techniques and peri-operative management of critically ill children and adults with congenital heart disease, allowing these professionals to anticipate, prevent or else treat such pathologies. The book will cover specific cardiac lesions, review their anatomy, pathophysiology, current preoperative, intraoperative and postoperative assessment and management; medical and surgical complications will be briefly described with each lesion further discussed in specific chapters. In addition, the book will have dedicated chapters to management of cardiac patients on extracorporeal membrane oxygenation, hemofiltration, hemo or peritoneal dialysis and plasma exchange. Practical guidelines for cardiovascular nursing care will be also included.
Intermediate filaments (IFs), in concert with microfilaments (MFs) and microtubules (MTs), form the cytoskeleton, and each of these fibrillar networks exhibits rather unique structural and functional characteristics. Intermediate filaments were discovered in eukaryotic cells in the late 1960s, and their name comes from the fact that their diameter is intermediate between MFs and MTs. In contrast to the latter, IFs constitute a network that extends from the nuclear envelope throughout the cytoplasm, and in many cases, interact with cell surface domains involved in cell-cell and cell- matrix interactions. Several key features of their expression, assembly, structure and dynamics are highlighte...