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Explores the Newly Discovered Link Between Nutrition and EpigeneticsCurrent research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigene
This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.
Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians will be more capable of explaining the mechanisms of gene expression regulation to their patients to reassure them about new drug developments that target chromatin signaling mechanisms. For example, several epigenetic drugs that act on chromatin signaling factors are in clinical trials or even approved for usage in cancer treatments, Al...
The world is on the verge of receiving new life forms that will profoundly and irrevocably change the global economy: the "gene hunters" who first cloned the gene in 1973 are now not only modifying existing species but also creating new plants and animals. Ready or not for such awesome power, the human race has put itself in a position to govern evolution. What will we do with the abilities we now command? asks this broad and stimulating book on the role of plant material in economic development. Writing in a style that is easily understandable even to those with no background in biotechnology, Calestous Juma begins by showing how the importation of plants strengthened the British Empire and...
Describes the authority, structure, functions, frequency of meetings, and membership of the NIH advisory committees.
A guide to federal, congressional, state, county and city health agencies and officials. Includes congressional standard, select, and joint committees, key health subcommittees, and delegations. Also includes federal health agencies, and state county and city health officials.
Dr Francis S. Collins, head of the Human Genome Project, is one of the world's leading scientists, working at the cutting edge of the study of DNA, the code of life. Yet he is also a man of unshakable faith in God. How does he reconcile the seemingly unreconcilable? In THE LANGUAGE OF GOD he explains his own journey from atheism to faith, and then takes the reader on a stunning tour of modern science to show that physics, chemistry and biology -- indeed, reason itself -- are not incompatible with belief. His book is essential reading for anyone who wonders about the deepest questions of all: why are we here? How did we get here? And what does life mean?