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Epicardial Adipose Tissue
This book is the first authoritative and comprehensive volume dedicated to epicardial adipose tissue (EAT). It provides an up-to-date and highly illustrated synopsis of the anatomical, biomolecular, genetic, imaging features, and clinical applications of EAT and its role in cardiovascular disease. It relays to the reader a contemporary view of the emerging interplay between the heart and adiposity-related diseases. In addition, this volume discusses the clinical implications and therapeutic targets of EAT in atrial fibrillation, heart failure and coronary artery disease. Comprehensive yet focused, Epicardial Adipose Tissue: From Cell to Clinic is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.
Drug-drug Interactions in the Metabolic Syndrome
This book reports updated data from the literature on potential drug-drug interactions occurring between drugs used to treat each individual disease of the metabolic syndrome. The manual is focused on metabolic syndrome drugs. Possible drug-drug interactions and their potential mechanisms are summarised and discussed. Chemical characteristics and mechanisms of action of each drug are also briefly described. Some new anti-obesity, anti-diabetes, lipid lowering and anti-hypertensive drugs were also reported and briefly discussed.
Inter-University Cooperation
Inter-university cooperation across the world has shown several positive outcomes in terms of knowledge exchange as well as R&D benefits. This book portrays best practices of inter-university cooperation between Italian and American universities, while featuring agreements of Sapienza University of Rome. This book presents conceptual and implementation specifics of cooperation, policy perspectives, as well as a selection of framework agreements of current cooperation initiatives. Aimed at university professors, education and R&D policy makers, this book shall prove worthy as a guideline to initiate and implement inter-university cooperation globally.
Adipokines
Adipokines (also called adipocytokines) are a group of peptides secreted by adipose tissue. They have diverse roles, from functions in the individual cell to the whole body. This volume examines a wide range of specific adipokines as well as their general cellular aspects, including thermal stress and adipokine expression, central nervous system ro
From Obesity to Diabetes
Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
Obesity and Cardiovascular Disease
This essential book comprehensively covers the diagnosis, treatment and management of cardiovascular disease in obese patients, translating up-to-date clinical research findings into clinical practice.
Obesity and the Kidney
We are currently facing an alarming obesity epidemic, with its well-known health consequences such as metabolic syndrome / type 2 diabetes, cardiovascular diseases, an increased incidence of certain types of cancer, musculoskeletal disorders and pulmonary diseases. Experimental and clinical evidence accumulated in recent years now suggests that obesity has also a major effect on renal structure and function. Since the adipocyte is considered a source of many hormones and cytokines, obesity has much more direct influences on renal function besides mediating hypertension: It can by itself induce renal disease such as focal segmental glomerulosclerosis, but also, more commonly, bring about prog...
Obesity
This comprehensive textbook addresses one of the major public health concerns of our era – obesity. Clearly and simply, Obesity: science to practice provides a balanced, coherent account of obesity: how to define and measure it, its epidemiology, the physiological basis, associated diseases, how to assess, manage and treat it, and also strategies for prevention. The book is generously illustrated, including graphs and flow charts for easy reference. The chapters cite key references so that interested readers may pursue a given topic in more detail. Well presented and thoroughly edited by one of the leading experts in the field, this is the textbook of choice for anyone working in obesity.
Emergency laparoscopic surgery in the elderly and frail patient
The global population is aging rapidly, and as a result emergency abdominal surgery for acute abdomen in the elderly has become a global issue. Demographic changes in the population have also altered the profile of emergency abdominal surgery, with typical causes of acute abdomen in the elderly including acute cholecystitis, incarcerated hernia, bowel obstruction and appendicitis. In these patients, recovery from surgery is often complicated, leading to longer hospital stays compared with younger patients. Laparoscopy in the emergency setting is well established and offers a number of advantages over open surgical approaches, such as reduced postoperative pain, length of hospital stay and co...
Medical Image Analysis and Informatics
With the development of rapidly increasing medical imaging modalities and their applications, the need for computers and computing in image generation, processing, visualization, archival, transmission, modeling, and analysis has grown substantially. Computers are being integrated into almost every medical imaging system. Medical Image Analysis and Informatics demonstrates how quantitative analysis becomes possible by the application of computational procedures to medical images. Furthermore, it shows how quantitative and objective analysis facilitated by medical image informatics, CBIR, and CAD could lead to improved diagnosis by physicians. Whereas CAD has become a part of the clinical wor...
