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First published in 1989. Routledge is an imprint of Taylor & Francis, an informa company.
It is vital to have knowledge of the neuroanatomical structures and functional neurological mechanisms, which are disrupted in neurogenic speech/language, disordered persons in order to understand the speech/language deficits themselves. This book provides a comprehensive coverage of the neurological basis of both the clinically recognised forms of aphasia and the various motor speech disorders, in both children and adults. It also covers more recently recognised language disorders, such as Parkinsons and related diseases, right hemisphere damage, closed-head injury, dementia, etc. This is a perfect text for practitioners who need to understand the integration of neuroanatomy and functional neurology with the practice of speech-language pathology.
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This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal, over many months. This is the first time that all of these expert contributions are presented in one place.Reliable methods for measuring OSS in organisms are essential. These would, amongst other things, offer applications as early warning signals for cancer and heart disease - eventually giving a range of measurable oxidation products best related to any given disease state.Additional observations relevant to OSS include: how much do measures of OSS vary in a group of humans? Does OSS decrease as a result of life-change factors and does it increase with age? With disease? With stress? Can a non-invasive, reliable, reputable measure of OSS be identified?This informative book provides the reader with the latest status of studies into OSS, currently used examples of BOSS, and answers to at least some of the questions posed above.
The complex roles of glutathione and sulfur amino acids in human health Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorp...