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This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Evaluates the most useful models for categorical and limited dependent variables (CLDVs), emphasizing the links among models and applying common methods of derivation, interpretation, and testing. The author also explains how models relate to linear regression models whenever possible. Annotation c.
This book highlights the state of the field in the new, provocative line of research into the cognition and behavior of the domestic dog. Eleven chapters from leading researchers describe innovative methods from comparative psychology, ethology and behavioral biology, which are combined to create a more comprehensive picture of the behavior of Canis familiaris than ever before. Each of the book’s three parts highlights one of the perspectives relevant to providing a full understanding of the dog. Part I covers the perceptual abilities of dogs and the effect of interbreeding. Part II includes observational and experimental results from studies of social cognition – such as learning and so...
Presenting a dynamic investigation into the role of the lexicon in syntactic theory, this book provides an insightful overview and introduction to lexical theory. It discusses the nature of argument and structure and debates the relation of argument nature to constituent structure and binding theory.
Praise for the Fourth Edition: "This book is . . . an excellent source of examples for regression analysis. It has been and still is readily readable and understandable." —Journal of the American Statistical Association Regression analysis is a conceptually simple method for investigating relationships among variables. Carrying out a successful application of regression analysis, however, requires a balance of theoretical results, empirical rules, and subjective judgment. Regression Analysis by Example, Fifth Edition has been expanded and thoroughly updated to reflect recent advances in the field. The emphasis continues to be on exploratory data analysis rather than statistical theory. The...
This two-volume set constitutes the refereed proceedings of the workshops which complemented the 21th Joint European Conference on Machine Learning and Knowledge Discovery in Databases, ECML PKDD, held in September 2021. Due to the COVID-19 pandemic the conference and workshops were held online. The 104 papers were thoroughly reviewed and selected from 180 papers submited for the workshops. This two-volume set includes the proceedings of the following workshops:Workshop on Advances in Interpretable Machine Learning and Artificial Intelligence (AIMLAI 2021)Workshop on Parallel, Distributed and Federated Learning (PDFL 2021)Workshop on Graph Embedding and Mining (GEM 2021)Workshop on Machine L...
Vulnerability to natural disasters continues to increase, severely compromising the achievement of poverty alleviation goals in many developing countries. A more effective approach is needed to reduce the impacts of these disasters. This publication proposes an approach that integrates ecosystem management, development planning and risk reduction strategies to reduce disaster impacts and improve both livelihoods and biodiversity outcomes.
This comprehensive study of the intersection of death and religion offers a unique look at how religious people approach death in the twenty-first century. Previous scholarship has largely focused on traditional beliefs and paid little attention to how religious traditions evolve in relation to their changing social context. Employing a sociological approach, "Death and Religion in a Changing World" describes how people from a wide variety of faiths draw on and adapt traditional beliefs and practices as they deal with death in modern societies. The book includes coverage of newly emerging social and religious phenomena that are only just beginning to be analyzed by religion scholars, such as public shrines, the role of the media, spiritual bereavement groups, and the use of the Internet in death practices.