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The mechanism by which cigarette smoke causes or contributes to inflammatory diseases like chronic obstructive pulmonary disease, cardiovascular disease and cancer remains unclear. Recent developments in our knowledge of cellular signaling suggest that cigarette smoke may cause oxidative stress in cellular systems. The assessment, consequences and possible modulation of these effects are discussed in this book which will interest oncologists and researchers in Biochemistry.
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
One word strikes more fear into a person’s mind than any other: CANCER. The physical, mental, emotional, and financial toll that comes with a cancer diagnosis is immense and affects not only cancer patients but also families and entire communities. This year alone approximately 600,000 Americans will lose their lives to cancer, and the forecast shows no signs of improving. Recent estimates tell us that 41 percent of all Americans will be diagnosed with cancer during their lifetimes and 21 percent of the population will lose their lives to this devastating disease. Cancer has evolved into a national crisis that touches each and every one of us. The vast majority of individuals who lose the ...
Vitamin C (ascorbic acid) is a key vitamin to animals and plants. This book looks at all aspects of vitamin C; its chemical and biochemical properties, its role in various plants and animals and its effect on our health. Written by an international team of experts, together they represent much of the expertise on vitamin C throughout the world.
Oxidative stress is one of the major symptoms accompanying physiological functions and numerous diseases. Oxidants and free radicals are connected with diseases such as cancer, diabetes, infectious, cardiovascular and neurodegenerative diseases and also in the aging process itself. Therefore, comprehensive knowledge of the underlying mechanisms of oxidant and free radical production and the defence against this permanent threat to cells is important for the understanding of many physiological and pathophysiological processes. This book overviews the basic mechanisms of oxidant formation and antioxidant defences. In addition, the formation of oxidants and their detoxification, the damage of macromolecules and the major repair and removal systems will be highlighted.
Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and t...
Presents a collection of more than sixty dessert recipes that use olive oil instead of butter, shortening, or margarine.
Natural antioxidants and food quality in atherosclerosis and cancer prevention provides a comprehensive and up-to-date overview of the role of natural antioxidants and lipid peroxidation in atherosclerosis and cancer. The book presents important information on the presence of various flavonoids found in berries, vegetables and fruits and their antioxidative potencies, as well as the role of antioxidative vitamins and carotenoids in cardiovascular diseases and cancer. In addition, the measurement of oxidative stress in humans is surveyed.
Advances in Chromatography is a venerable series that has reported on the latest state-of-the-art developments in the field for the past four decades. The newest installment, Volume 49, continues the tradition of compiling the work of expert contributors who present timely and cutting edge reviews of current and emerging methods and applications in this dynamic field. Highlights in this edition include: The hyphenation of liquid chromatography with mass spectrometry in order to determine oligonucleotide adducts as markers for cancer Glycoproteomics and the glycosylation of proteins, addressing biomarkers in different types of diseases Chiral separation, an important area particularly in the ...