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Essentials of Cerebellum and Cerebellar Disorders
  • Language: en
  • Pages: 694

Essentials of Cerebellum and Cerebellar Disorders

This monograph, now in its 2nd edition with 31 new chapters and significant updates, is the first book of its kind written specifically for graduate students and clinicians. The monograph is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013; 2nd edition: 2022), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology and related areas. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. Essentials of the Cerebellum and Cerebellar Disorders makes this large and expanding body of knowledge readily accessibl...

Mechanisms and Emerging Therapies in Tremor Disorders
  • Language: en
  • Pages: 556

Mechanisms and Emerging Therapies in Tremor Disorders

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in ...

Autoimmunity and the Brain: Paraneoplastic Neurological Injury and Beyond
  • Language: en
  • Pages: 136

Autoimmunity and the Brain: Paraneoplastic Neurological Injury and Beyond

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Trials for Cerebellar Ataxias
  • Language: en
  • Pages: 716

Trials for Cerebellar Ataxias

Despite the critical importance of the cerebellum in brain function, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference, and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.

GABA And Glutamate
  • Language: en
  • Pages: 139

GABA And Glutamate

This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.

Japanese Private International Law
  • Language: en
  • Pages: 336

Japanese Private International Law

  • Categories: Law

This is the leading reference on Japanese private international law in English. The chapters systematically cover the whole of Japanese private international law, not just questions likely to arise in commercial matters, but also in family, succession, cross-border insolvency, intellectual property, competition (antitrust), and environmental disputes. The chapters do not merely cover the traditional conflict of law areas of jurisdiction, applicable law (choice of law), and enforcement. The chapters also look into conflict of law questions arising in arbitration and assess Japanese involvement in the global harmonisation of private international law. In addition to summarising relevant principles and scholarly views, the authors discuss case law whenever possible and identify deficiencies and anticipate difficulties in the existing law. The book thus presents the Japanese conflict of laws through a combination of common and civil law analytical techniques and perspectives, providing readers worldwide with a more profound and comprehensive understanding of the subject.

Wearable Technologies
  • Language: en
  • Pages: 270

Wearable Technologies

This edited volume Wearable Technologies is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of computer engineering. The book comprises single chapters authored by various researchers and edited by an expert active in the computer engineering research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts.

Pedagogical Approaches to Intercultural Competence Development
  • Language: en
  • Pages: 200

Pedagogical Approaches to Intercultural Competence Development

Globalization has triggered an increased need to extend linguistic and cultural awareness into action from our daily encounters to our professional interactions. As our communities continuously grow into linguistically and culturally rich environments, so, too, should our pedagogical and research approaches. Specifically, this volume provides an overview of pedagogies and research methodologies that reflect the urgent need to develop intercultural competence in diverse professions including (but not limited to) law, medicine, business, foreign and second language instruction, and communications. The book re-examines and highlights pedagogical and research approaches to intercultural competence development across disciplines, paving the way to promote collaborative efforts and reassess the critical role of intercultural competence development in distinct fields.

Recent advances and challenges in cancer immunotherapies for patients with autoimmune diseases
  • Language: en
  • Pages: 133