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This volume contains contributions by some of the leading scientists in the field of thiol oxidation/reduction (redox) biochemistry. It is focused on the biological/pathophysiological implications of newly-discovered functions of cellular thiols, such as glutathione in the first place.
The Crustacea is one of the dominant invertebrate groups, displaying staggering diversity in form and function, and spanning the full spectrum of Earth's environments. Crustaceans are increasingly used as model organisms in all fields of biology, as few other taxa exhibit such a variety of body shapes and adaptations to particular habitats and environmental conditions. Physiology is the fourth volume in The Natural History of the Crustacea series, and the first book in over twenty-five years to provide an overview of the comparative physiology of crustaceans. An understanding of physiology is crucial to a comprehension of the biology of this fascinating invertebrate group. Written by a group of internationally recognized experts studying a wide range of crustacean taxa and topics, this volume synthesizes current research in a format that is accessible to a wide scientific audience.
This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free...
This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses. Other chapters review glutathione transport systems and glutathione peroxidases and their differences in substrate specificities and localization. Further contributions center on the diversified roles of different glutathione-S-transferases and the roles of nitrosoglutathione and glutaredoxins - a subfamily of redoxins. The book closes with discussions of the analogous or homologous thiol metabolism in pathogens and the potential suitability of involved en...
Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxi...
Free Radicals in Biology, Volume V covers the mechanisms for the generation of free radicals. This volume contains eight chapters that discuss the biology and chemistry of oxy-radicals in mitochondria and the radical-mediated metabolism of xenobiotics. The opening chapter describes the mechanisms of free radical production in enzymatically promoted lipid peroxidation, generally in microsomes or microsomal lipids. The subsequent chapters explore the biochemistry and biology of plant and animal lipoxygenases; the production of superoxide and hydrogen peroxide in mitochondria; and the biological role of these species in mitochondria and related systems. The discussions then shift to the effects...
Named after Selene, Greek goddess of the moon, selenium (Se) has moved has moved from being thought of as a toxicant to being considered an essential nutrient with the potential to reduce cancer risk in the span of seven decades. Diversity of Selenium Functions in Health and Disease focuses on current knowledge of aspects of Se research relevant to
As we enter the new millennium, promoting sound mental health and positive behavior of adolescents has undeniably taken on greater significance than ever before. To that end, more and more research is confirming what many have suspected for years: environment and community surroundings have a major affect on an adolescent’s well-being and overall mental health. And because no single causal agent triggers teenage pathology—and no one-size-fits-all treatment is available—the Handbook of Adolescent Behavior Problems offers a comprehensive and integrative biopsychosocial approach to effective practice. This volume examines not only the psychological and genetic factors underlying dysfuncti...
Ancients traveled far and paid handsomely to hear the sibyls and oracles channel wisdom from the gods. The Holy Bible writes of many prophets and seers, but divination by ordinary people was strongly prohibited. As a result, mediums and psychics have since been laughed at, ostracized, and even burned at the stake. But always there have been some people who persisted in believing in spirit communication secretly. We must take a sober and realistic view of divination in the times ahead, but openly and publicly. This book will help you to understand divination for its true value. Listening to the spirit world is our only hope for a world of peace.
This volume provides a graduate-level introduction to communication science, including theory and scholarship for masters and PhD students as well as practicing scholars. The work defines communication, reviews its history, and provides a broad look at how communication research is conducted. It also includes chapters reviewing the most frequently addressed topics in communication science. This book presents an overview of theory in general and of communication theory in particular, while offering a broad look at topics in communication that promote understanding of the key issues in communication science for students and scholars new to communication research. The book takes a predominantly...