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This book contains a selection of papers presented at APME '99 ( Third International Symposium on Advanced Polymers via Macromolecular Engineering --- Colonial Williamsburg, VA, USA, July/August 1999). The book focuses on the synthesis of targeted polymers with specific properties using macromolecular architecture. Various controlled polymerization
The Ups and Downs in Drug Design: Adventures in Medicinal Chemistry highlights the necessity for an integrative approach in medicinal chemistry and chemical biology. As medicinal chemistry is not a monolithic science, it is important to emphasize the other various disciplines that are required for successful drug design. This book presents the author’s own personal experience in this field and describes the "ups" and "downs" that come with drug discovery. It is an excellent companion text for graduate and postgraduate students who would like further insight into the parameters of drug design, including the challenges that come with the project. Key Features Illustrates "real-life" examples in medicinal chemistry Integrates the use of physical, chemical, and biological concepts that are important in drug design Highlights the "ups" and "downs" that come with drug discovery Aims to inspire students who may be struggling with the challenges and thought process in drug design Intends to be an excellent companion text for graduate and postgraduate students
Neurointerventional Techniques: Tricks of the Trade is a practical reference that includes core procedures used in the growing neurointerventional subspecialty. The step-by-step, concise presentation of procedures along with original line drawings and high-quality images concisely distill a wealth of information, making it easy for both novice and expert neurointerventionists to review how procedures are performed. The book includes over 50 specific procedures as well as important chapters on access points, physiological testing, and pharmacology in the endovascular suite. Key Features: Written by leading experts in neurointerventional practice Strong emphasis on complication avoidance throu...
This volume provides a state-of-the-art review of the key aspects of HBV. It covers our current understanding of the HBV genome and lifecycle, liver-enriched factors in the regulation of HBV transcription and translation, HBV protein structures and biological functions, and the immunology and pathogenesis of HBV. It also provides an update on cell and animal models, as well as molecular approaches. The respective chapters also cover the clinical management of hepatitis B and discuss future research directions, in particular, the identification of molecular targets for pharmacological intervention. Given its scope, the book offers a valuable resource for students, researchers, clinicians, and health practitioners in the fields of virology, infectious disease, public health etc. Dr Hong Tang is a Professor and Director of the Center of Infectious Diseases, West China Hospital of Sichuan University.
This book shows impressively how complex mathematical modeling of materials can be applied to technological problems. Top-class researchers present the theoretical approaches in modern mechanics and apply them to real-world problems in solid mechanics, creep, plasticity, fracture, impact, and friction. They show how they can be applied to technological challenges in various fields like aerospace technology, biological sciences and modern engineering materials.
The effects of inadequate diets on the population include malnutrition, non-communicable diseases and obesity. 'Hidden hunger', also known as micronutrient deficiencies, leads to various health-related disorders and diseases. Indigenous plants, in the form of indigenous fruits and leafy vegetables are gaining interest as a source of nutrients and bioactive phytochemicals, satisfying both food demand and health needs. Moreover, with the impact of climate change, and the importance of sustainability of food systems, it is essential that we investigate new, forgotten and alternative crops that can thrive in harsh conditions, require low fertilizer input, and are easily harvestable. This is an essential resource for academic researchers and industry professionals in the fields of horticulture, agriculture, crop science, human health and nutrition.