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Local governments encounter many problems, and although there is not one panacea that works internationally, this book argues that there are mechanisms to improve local situations. By drawing on case studies from the developing world, the authors review best practices in good governance.
This book describes up-to-date information on the pathogenesis and molecular biology of human papillomaviruses and describes the mechanistic role of the viruses in epithelial cancers. Included in the book are chapters on the epidemiology of human papillomaviruses, the factors that control replication and transcription and the viral proteins, which are involved in modulating the biology of the host cell leading to cancer. Details of the immune response to the viruses and potential vaccine strategies are discussed.
A Vast Sky is an anthology of contemporary world haiku from 2000-2014. It is the most comprehensive anthology of its kind, with generous selections by established editors of Japan, Europe, North and South America, the Caribbean, New Zealand, Australia, India, Africa, etc. It includes insightful introductions to the history and poetics of haiku in its four major sections: Japan, Europe, The New World, and The Rest of the World. It includes up-to-date sources for contemporary world haiku.
Perhaps the first novel to take as its subject the appreciation and crafting of haiku, this is the story of Buck-Teeth, a provincial poet and fictitious student of the Japanese classical haiku master Issa, who, in the course of his training, travels to ancient Edo and contemporary New Orleans, falls in and out of love, considers the many schools of haiku, and ultimately learns what it is to be a poet. Along the way we are offered gentle lessons on haiku and what we might put into it, how it and we got this way, and what it all might mean.
Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging regulatory issues that will govern clinical use of NGS, and reimbursement paradigms that will affect the way in which laboratory professionals get paid for the testing. - Simplifies complexities of NGS technologies for rapid education of clinical genomicists and genomic pathologists towards genomic medicine paradigm - Tried and tested practice-based analysis for precision diagnosis and treatment plans - Specific pipelines and meta-analysis for full range of clinically important variants
Cognitive linguists have proposed that metaphor is not just a matter of language but of thought, and that metaphorical thought displays a high degree of conventionalization. In order to produce converging evidence for this theory of metaphor, a wide range of data is currently being studied with a large array of methods and techniques. Finding Metaphor in Grammar and Usage aims to map the field of this development in theory and research from a methodological perspective. It raises the question when exactly evidence for metaphor in language and thought can be said to count as converging. It also goes into the various stages of producing such evidence (conceptualization, operationalization, data collection and analysis, and interpretation). The book offers systematic discussion of eight distinct areas of metaphor research that emerge as a result of approaching metaphor as part of grammar or usage, language or thought, and symbolic structure or cognitive process.
This book presents new and innovative ideas on the didactics of translation and interpreting. They include assessment methods and criteria, assessment of competences, graduate employability, placements, skills labs, the perceived skills gap between training and profession, the teaching of terminology, and curriculum design.