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Cholesterol Homeostasis
This volume provides state-of-the-art techniques for studying various aspects of cholesterol homeostasis, including its uptake, synthesis and efflux from the cell, as well as its trafficking within the cell. Chapters also cover techniques for studying the regulation of cholesterol homeostasis at both the transcriptional and post-translational levels, as well as studying the membrane topology and structure of cholesterol-related proteins. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cholesterol Homeostasis: Methods and Protocols aims to provide key techniques in tackling the investigation of cholesterol homeostasis.
Like Water on Stone
What is deja vu? Is it simply a sense that something has already happened? Or does it mean that some plan is in motion? And what would it mean if life came to seem like a constant deja vu? Would this imply that free will is an illusion? Don Pierce is a scientist who values gritty experiment over beautiful theory and sees no worth in pretty stories about the meaning of things. Yet the closed egg of his life cracks open and frees him. On a business trip to Australia, Don begins to see visions of the Aboriginal Dreamtime. He is compelled to accept that visions can have overwhelming force - and that the past pervades the present."
Sharing Lives
Sharing Lives explores the most important human relationships which last for the longest period of our lives: those between adult children and their parents. Offering a new reference point for studies on the sociology of family, the book focuses on the reasons and results of lifelong intergenerational solidarity by looking at individuals, families and societies. This monograph combines theoretical reasoning with empirical research, based on the Survey of Health, Ageing and Retirement in Europe (SHARE). The book focuses on the following areas: ● Adult family generations, from young adulthood to the end of life, and beyond ● Contact, conflict, coresidence, money, time, inheritance ● Cons...
So You Want to Be a Neuroscientist?
The pursuit to understand the human brain in all its intricacy is a fascinatingly complex challenge and neuroscience is one of the fastest-growing scientific fields worldwide. There is a wide range of career options open to those who wish to pursue a career in neuroscience, yet there are few resources that provide students with inside advice on how to go about it. So You Want to Be a Neuroscientist? is a contemporary and engaging guide for aspiring neuroscientists of diverse backgrounds and interests. Fresh with the experience of having recently launched her own career, Ashley Juavinett provides a candid look at the field, offering practical guidance that explores everything from programming...
Design and Analysis of Vaccine Studies
As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.
Abnormal Illness Behaviour
Pilowsky presents a general introduction to the early recognition and management of abnormal illness behaviour, and suggests ways to identify such behaviour, offer appropriate psychological care and provide specialist psychiatric help.
Comparative Literature
This book serves several purposes, all very much needed in today's embattled situation of the humanities and the study of literature. First, in Chapter One, the author proposes that the discipline of Comparative Literature is a most advantageous approach for the study of literature and culture as it is a priori a discipline of cross-disciplinarity and of international dimensions. After a "Manifesto" for a New Comparative Literature, he proceeds to offer several related theoretical frameworks as a composite method for the study of literature and culture he designates and explicates as the "systemic and empirical approach." Following the introduction of the proposed New Comparative Literature,...
Innovation for Sustainability
The aim of this edited book is to provide a comprehensive overview of the opportunities and challenges related to innovation for sustainability. Combining work from both emerging and established scholars in different academic fields, this book provides an integrated understanding of the topic from four perspectives. First, the big picture: frameworks, types, and drivers; second, strategy and leadership; third, measurement and assessment and fourth, tools, methods and technologies. Chapter 11 of this book is available open access under a CC BY 4.0 license at link.springer.com. The editors donate their remuneration for this book to conservation organisation the WWF.
Shrinks
The inspiration for the PBS series Mysterious of Mental Illness, Shrinks brilliantly tells the "astonishing" story of psychiatry's origins, demise, and redemption (Siddhartha Mukherjee). Psychiatry has come a long way since the days of chaining "lunatics" in cold cells and parading them as freakish marvels before a gaping public. But, as Jeffrey Lieberman, MD, the former president of the American Psychiatric Association, reveals in his extraordinary and eye-opening book, the path to legitimacy for "the black sheep of medicine" has been anything but smooth. In Shrinks, Dr. Lieberman traces the field from its birth as a mystic pseudo-science through its adolescence as a cult of "shrinks" to it...
