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Environmental Endocrinology and Endocrine Disruptors
This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and o...
Mechanics and Thermomechanics of Rubberlike Solids
This work gives for the first time an interdisciplinary and deep approach to the mathematical modelling of rubber-like materials considering both the molecular and phenomenological point of views. It contains an introduction to the suitable numerical techniques and an overview of experimental techniques and data with a short survey on some industrial applications. Elastic and inelastic effects are discussed in details. The book is suitable for applied mathematicians, mechanical engineers, civil engineers, material scientists and polymer scientists.
Frontiers in Anti-Infective Agents: Volume 5
Anti-infective agents are a distinct class of pharmacologically important molecules that has served mankind in different capacities to combat life-threating pathologic conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial and urinary anti-infective agents. However, evolutionary changes, adaptations and development of pathogenic microorganisms strains the therapeutic efficacy of these drugs thus limiting their clinical utility over the years. Frontiers in Anti-Infective Agents Volume 5 is a collection of notable research efforts, successful anti-infective drug development programmes and a comprehensive overview of the successes and failures of recent cl...
Cerebral Palsy
This book helps rehabilitators and caregivers understand the multifaceted needs of children with cerebral palsy or other neuromotor impairments in order to plan and implement an effective treatment regimen. Drawing on the authors’ extensive experience spanning several decades, it addresses the sensitive challenge of rehabilitation, which cannot and must not be confined by the rigid schemes of established schools. In particular, the book provides numerous practical suggestions, intended to guide the reader through correct clinical reasoning, setting goals and subsequent treatment. Furthermore, it includes chapters on evaluating and treating the upper limbs, feeding and communication problems, as well as on the care of soft tissues and the management of the visual difficulties in these children. The book is a valuable resource for physiotherapists, occupational therapists, speech therapists and other caregivers.
Modulation of Oxidative Stress
Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological and physicochemical perspectives. The book is comprised of three main parts, with the first discussing the biochemical aspects of oxidative stress modulation. Other sections cover physiological and pathophysiological aspects on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer's disease, liver transplant, and cancer. Final content is dedicated to pharmacological aspects and includes ...
Miombo Woodlands in a Changing Environment: Securing the Resilience and Sustainability of People and Woodlands
Based on work by the Miombo Network in southern Africa, this book helps decision-makers and general readers alike improve their understanding of the socio-ecology of the Miombo woodlands across southern Africa. It also highlights the importance of and the need for further research on the unique Miombo ecology and its link with economic development. One major challenge facing these woodlands is the influence that direct (both natural and anthropogenic) and indirect drivers of change, as well as interactions between these, have had over the centuries. As such the book explores the socio-economic and ecological interactions that occur in these woodlands and discusses the need for further resear...
Hereditary Chorioretinal Disorders
This volume of the retina atlas focuses on hereditary chorioretinal disorders. The topics covered include retinitis pigmentosa, Best disease, congenital X-linked retinoschisis, cone dystrophy, Stargardt’s disease, pattern dystrophy, North Carolina macular dystrophy, choroideremia, Mallattia Leventinese, Bietti’s crystalline dystrophy, and albinism. All clinical features are clearly illustrated with multimodal imaging techniques. The utility of some of the latest imaging tools such as OCT angiography, adaptive optics-scanning laser ophthalmoscopy, and microperimetery is discussed. Readers will gain valuable new insights into pathogenesis at the molecular level, which have been facilitated...
Contact Problems in Elasticity
The contact of one deformable body with another lies at the heart of almost every mechanical structure. Here, in a comprehensive treatment, two of the field's leading researchers present a systematic approach to contact problems. Using variational formulations, Kikuchi and Oden derive a multitude of new results, both for classical problems and for nonlinear problems involving large deflections and buckling of thin plates with unilateral supports, dry friction with nonclassical laws, large elastic and elastoplastic deformations with frictional contact, dynamic contacts with dynamic frictional effects, and rolling contacts. This method exposes properties of solutions obscured by classical meth...
The Emerging Science of Homeopathy
In this updated reissue of their classic Homeopathy: A Frontier in Medical Science, Italian physicians Paolo Bellavite and Andrea Signorini thoroughly examine previous and current literature on the science of homeopathy in order to discover answers to the elemental questions about homeopathy. Bellavite and Signorini engage in a fascinating discussion of the biophysics of water, biological effects of electomagnetic fields, chaos theory, and fractals.
Advances in Lignocellulosic Biofuel Production Systems
Advances in Lignocellulosic Biofuel Production Systems focuses on general topics such as novel pretreatment strategies, lignocellulosic biomass as a suitable feedstock for biofuels, lifecycle assessment and integrated biorefineries. Furthermore, the book focuses on more advanced topics such as genetically engineered feedstocks, metabolically engineered microbes, bioreactor design and configuration, cell immobilization strategies, artificial intelligence applications and nanotechnology. This book will guide readers through all aspects of lignocellulosic biofuel production rather than simply covering a single topic. - Provides information on the most advanced and innovative technologies for bi...
