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Malaria Transmission Biology
The malaria parasite life cycle is complex and includes an obligatory developmental stage in its mosquito vector host. This transition from human-host to mosquito-host to human-host involves multiple developmental stages and divergent host tissues. Over the years, the research focus on the asexual stage parasites, which causes the symptoms of the disease, has transitioned towards a renewed focus on the transmission forms (or gametocytes), the only stages transmittable to the mosquito vector through ingestion of an infected blood meal. Analysis of sporozoite-liver interactions that result in the establishment of parasitic infection in the mammalian host has become an important research focus,...
Advances on the Gametocyte Biology, Host Immunity and Vector Stages to interrupt the Transmission of Malaria
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EU Research Fighting the Three Major Deadly Diseases
Shows the projects currently financed by the European Commission's Seventh Research Framework Programme (FP7) since 2007 up to 2010, aiming at combating these three major killer diseases: HIV/AIDS, Malaria and Tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America
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Kin Recognition in Protists and Other Microbes
Kin Recognition in Protists and Other Microbes is the first volume dedicated entirely to the genetics, evolution and behavior of cells capable of discriminating and recognizing taxa (other species), clones (other cell lines) and kin (as per gradual genetic proximity). It covers the advent of microbial models in the field of kin recognition; the polymorphisms of green-beard genes in social amebas, yeast and soil bacteria; the potential that unicells have to learn phenotypic cues for recognition; the role of clonality and kinship in pathogenicity (dysentery, malaria, sleeping sickness and Chagas); the social and spatial structure of microbes and their biogeography; and the relevance of unicells’ cooperation, sociality and cheating for our understanding of the origins of multicellularity. Offering over 200 figures and diagrams, this work will appeal to a broad audience, including researchers in academia, postdoctoral fellows, graduate students and research undergraduates. Science writers and college educators will also find it informative and practical for teaching.
Doenças infecciosas e parasitárias no contexto brasileiro – Volume 4
O que lhe vem à mente ao ler o termo “doenças infecciosas e parasitárias”? E se adicionarmos “no contexto brasileiro” – sua resposta mudaria? É certo que as doenças infecciosas e parasitárias (DIP) não escolhem alvos, mas sabemos que as condições climáticas, socioeconômicas e sanitárias do Brasil tornam nosso país e, em especial, determinados grupos populacionais, mais vulneráveis a elas. Em certa medida, sabemos o que precisa ser feito para diagnosticar, tratar, combater e prevenir as DIP. Porém, mesmo uma base científica sólida pode ser insuficiente para impedir os danos causados por um patógeno e a doença a ele associada. Em algum nível seremos afetados; e, para minimizar o impacto do desconhecido, a busca por conhecimento deve ser contínua. Neste cenário, temos o prazer de apresentar a obra “Doenças Infecciosas e Parasitárias no Contexto Brasileiro” em dois novos volumes, os quais reúnem mais de 50 capítulos que agregam conhecimentos atualizados sobre as mais diversas DIP. Esperamos que esta obra seja lida como um referencial, que fomente ideias, promova debates e seja vista como exemplo de força da produção científica nacional.
