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The Society of Genes
Nearly four decades ago Richard Dawkins published The Selfish Gene, famously reducing humans to “survival machines” whose sole purpose was to preserve “the selfish molecules known as genes.” How these selfish genes work together to construct the organism, however, remained a mystery. Standing atop a wealth of new research, The Society of Genes now provides a vision of how genes cooperate and compete in the struggle for life. Pioneers in the nascent field of systems biology, Itai Yanai and Martin Lercher present a compelling new framework to understand how the human genome evolved and why understanding the interactions among our genes shifts the basic paradigm of modern biology. Contr...
The Society of Genes
Nearly four decades ago Richard Dawkins published The Selfish Gene, famously reducing humans to “survival machines” whose sole purpose was to preserve “the selfish molecules known as genes.” How these selfish genes work together to construct the organism, however, remained a mystery. Standing atop a wealth of new research, The Society of Genes now provides a vision of how genes cooperate and compete in the struggle for life. Pioneers in the nascent field of systems biology, Itai Yanai and Martin Lercher present a compelling new framework to understand how the human genome evolved and why understanding the interactions among our genes shifts the basic paradigm of modern biology. Contr...
Power Laws, Scale-Free Networks and Genome Biology
Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the problems in this field in a rigorous but not excessively mathematical manner and to represent different viewpoints, which is crucial in this emerging discipline. Each chapter includes, in addition to technical descriptions of properties of biological networks and evolutionary models, a more general and accessible introduction to the respective problems. Most chapters emphasize the potential of theoretical systems biology for discovery of new biological phenomena.
The Knowledge Machine: How Irrationality Created Modern Science
“The Knowledge Machine is the most stunningly illuminating book of the last several decades regarding the all-important scientific enterprise.” —Rebecca Newberger Goldstein, author of Plato at the Googleplex A paradigm-shifting work, The Knowledge Machine revolutionizes our understanding of the origins and structure of science. • Why is science so powerful? • Why did it take so long—two thousand years after the invention of philosophy and mathematics—for the human race to start using science to learn the secrets of the universe? In a groundbreaking work that blends science, philosophy, and history, leading philosopher of science Michael Strevens answers these challenging questi...
A Theory of Everyone
'Mind expanding - this book will change your view of the world forever' Matthew Syed A blueprint for a better future. Playing on the phrase "a theory of everything" in physics, Michael Muthukrishna offers a unified theory of human behavior, culture, and society - a theory of everyone. Drawing on the most recent research across the sciences, humanities, and the emerging field of cultural evolution, he paints a panoramic picture of who we are and exactly what makes human beings different from all other forms of life on the planet. Muthukrishna argues that it is our unique ability to create culture, a shared body of knowledge, skills, and experience passed on from generation to generation that ...
Mysterious Commonplace, The: A Life In Science
Acclaimed biomedical scientist Charles DeLisi tells the story of the rewards and frustrations of a life in science. The memoir spans half a century beginning in grade school when we find a somewhat shy boy deeply affected by the profoundly saddening sight of trees and woods in his beloved Bronx neighborhood being displaced by tons of steel and concrete. The reader is taken inside the mind of a complex non-conformist as he struggles with personal tragedy and ambivalence and moves from physics to history back to physics, and eventually into a career as a biomedical scientist. Among the most important parts of the memoir are his personal recollections of the years as director of the Department ...
We Alone
A thoughtful exploration of how humans have endangered the Earth but can pull it back from the brink, as told by a renowned conservationist This personal and thoughtful book by renowned Kenya conservationist David Western traces our global conquest from Maasai herders battling droughts in Africa to the technological frontiers of California. Western draws on a half century of research in the savannas and his own life’s journey to argue that conservation is not a modern invention. The success of all societies past and present lies in conservation practices, breaking biological barriers and learning to live in large cooperative groups able to sustain a healthy environment. Our ecological emancipation from nature enabled us to expand our horizons from conserving food and water for survival to saving whales, elephants, and our cultural heritage. In the Anthropocene, our scientific knowledge and modern sensibilities offer hope for combating global warming and creating a planet able to sustain the wealth of life, but only if we use our unique cultural capacity of cooperation to plan our future.
Behold the Man
After a substantial new essay examining the nature of a properly skeptical historical inquiry into Jesus of Nazareth in the context of contemporary worldviews, from pre-modernism to meta-modernism, Behold the Man presents revised essays on an eclectic range of issues: from how the Epistle of James treats Jesus as Divine within decades of the crucifixion, and an evaluation of recent arguments about the dating of the Fourth Gospel, to debunking claims about Jesus and “ancient aliens,” and furthering debate about the resurrection. With a foreword by eminent New Testament scholar Craig L. Blomberg, and extensive recommended resources, Behold the Man: Essays on the Historical Jesus represents a wide-ranging, interdisciplinary engagement with historical Jesus studies.
The Mindful Body
Learn how adjusting your thoughts can change your health—from the “mother of mindfulness” and first female tenured professor of psychology at Harvard. “What matters more: mind or body? Filled with original research and thought-provoking insights, The Mindful Body shows that the two are not just connected but are actually one, opening us to vast potential for health and happiness.”—Dan Ariely, New York Times bestselling author of Predictably Irrational Can changing your thoughts improve your health? We tend to live our lives as though our ailments—our stiff knees or frayed nerves or diminished eyesight—can change only in one direction: for the worse. Award-winning social psych...
Herding Hemingway's Cats
The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work? There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the ...
