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A Century at Sea
As World War One drew to a close, Christen Smith left the Royal Norwegian Navy to start his own shipping company. After a stumbling start, he succeeded in creating a totally new shipping segment: heavy-lift transport. Christen Smith’s vessels became the industry standard for ships lifting and carrying locomotives, railway cars, river boats and other heavy cargo that needed to be transported from one continent to another. One hundred years later, Belships has sailed through wars, upswings and downturns. After leaving the heavy-lift trade almost fifty years ago, the company has been involved in a broad range of shipping activities. Today, Belships is a significant player in the dry bulk segm...
Ancient Fortifications
Dedicated to the investigation of fortifications as important and integral elements of ancient built space, the present volume results from the activity of the German based international research network Fokus Fortifikation. Ancient Fortifications in the Eastern Mediterranean and is intended as a guide to research on ancient fortifications and a source of inspiration for new research. Ancient city walls and other fortification structures have long been underestimated. Since the early years of the 21st century, research on ancient fortifications has experienced an international boom, particularly amongst young researchers. They approached the study of fortifications with fresh ideas and new a...
Eukaryotic RNases and Their Partners in RNA Degradation and Biogenesis
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Pharmacology of Ocular Therapeutics
This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular drug therapy by compiling all key aspects of the pharmacology, toxicology, pharmaceutical science, ocular biochemistry and cell biology of these agents. Chapters detail drug transfer across barriers, systemic toxicity of topically applied drugs, autonomic drugs used for diagnostics, as well as anti-infl...
Liberalization in the Developing World
Liberalization in the Developing World compares the success of liberalization strategies in Asia, Africa and Latin America over the past decade. Three models emerge, corresponding to the three continents covered, which reflect the degree of state intervention in the economy and the success of the liberalization policies adopted. The conclusions drawn demonstrate that economic and political liberalization do not have to go hand in hand. On the contrary, the case studies presented in this volume show that the role of the state can be crucial in mobilizing both the human and capital investment needed to be able to compete in international economy.
The City of New Halos and its Southeast Gate
This volume presents a detailed description and analysis of the structure and layout of the Southeast Gate of New Halos, a Hellenistic city in Thessaly (Greece). The gate was excavated in the period 1995-2006. An impressive enceinte, 4.7 km long and fortified with at least 120 towers, surrounded the lower and upper town of Halos. Excavation of a series of houses in the lower town revealed that the city, probably founded in 302 BC by Demetrios Poliorketes, was abandoned after an earthquake around 265 BC. The Southeast Gate, flanked by two towers, gave accessto the city from the south. Numerous artefacts show that after the earthquake the gate complex was used as a large farmstead where agricultural produce was processed and stored. Today, the walls of this well-preserved courtyard gate still stand two to five metres above the bedrock.
Agricultural and Food Electroanalysis
Agricultural and Food Electroanalysis offers a comprehensive rationale of electroanalysis, revealing its enormous potential in agricultural food analysis. A unique approach is used which fills a gap in the literature by bringing in applications to everyday problems. This timely text presents in-depth descriptions about different electrochemical techniques following their basic principles, instrumentation and main applications. Such techniques offer invaluable features such as inherent miniaturization, high sensitivity and selectivity, low cost, independence of sample turbidity, high compatibility with modern technologies such as microchips and biosensors, and the use of exciting nanomaterials such as nanoparticles, nanotubes and nanowires. Due to the advantages that modern electroanalytical techniques bring to food analysis, and the huge importance and emphasis given today to food quality and safety, this comprehensive work will be an essential read for professionals and researchers working in analytical laboratories and development departments, and a valuable guide for students studying for careers in food science, technology and chemistry.
The Blood Brain Barrier (BBB)
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging...
Multiple Sclerosis Immunology
The availability of powerful genome-wide association study technology, during the last five years, has shown that most of the “new” MS susceptibility loci are immune-response genes. It is clear that there is much novelty in the field of MS immunology, which has served as an impetus to invest in new therapies. Notably, most if not all of these are immunotherapies. Even the equally exciting field of cell-based therapies and neuro-regeneration may well rely on cells or growth factors that are no less immunomodulators than restorative of myelin and neural cell function. Multiple Sclerosis Immunology looks at MS immunology as the basis for the present and—even more—the future of treatments for this complex autoimmune condition. Both editors are immunologists, as well as clinical neurologists, and appreciate the importance of a sustained dialogue between basic and clinical scientists to ensure that “translation” is real and not just virtual.
Toxicological Survey of African Medicinal Plants
Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxi...
