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Enlarged to describe more than a decade of advances in the immunotherapy of allergic diseases and asthma, this Third Edition contains the most recent studies on the mechanisms, manufacture, and standardization of various allergen groups and their utilization in the treatment of allergic diseases-containing 8 new chapters detailing various pharmacoe
Researchers and clinicians relate their experience with immunotherapy using antigens, which has remained important throughout the enormous advances in immunology over the past 30 years. Among the topics are a historical perspective, outdoor and indoor allergens, venoms, the preparation and administration of extracts, and reactions and other adverse effects. Annotation copyrighted by Book News, Inc., Portland, OR
The adoption of agriculture is one of the major developments in human history. Archaeological studies have demonstrated that the trajectories of Neolithisation in Northwest Europe were diverse. This book presents a study into the archaeology of the communities involved in the process of Neolithisation in the Lower Rhine Area (5500-2500 cal BC). It elucidates the role played by the indigenous communities in relation to their environmental context and in view of the changes that becoming Neolithic brought about. This work brings together a comprehensive array of excavated archaeological sites in the Lower Rhine Area. Their analysis shows that the succession of Late Mesolithic, Swifterbant cult...
This publication presents the results of the 2005-2007 excavations at Swifterbant S4, carried out by the Groningen Institute of Archaeology. S4 is a well-preserved Neolithic wetland site (c. 4300-4000 cal. BC) located within the Swifterbant river system in the Netherlands. We present the landscape setting, the various finds categories and the spatial patterns with three research themes in mind. Theme 1 concerns the environmental setting, subsistence and site function. We conclude that the Swifterbant hunter-gatherer-farmers exploited a mosaic-type landscape. Theme 2 deals with developments in site function during the occupation and exploitation history of the site. This analysis leads to the observation that episodes of cultivation and settlement alternated at S4. Theme 3, the use of space, was difficult to study due to the fragmented nature of the excavation plan. This site monograph makes Swifterbant S4 the most comprehensively published site of the Swifterbant river system.
This new collection of papers from leading experts provides an overview of cutting-edge research in Old World zooarchaeology. The research presented here spans various areas across Europe, Western Asia and North Africa – from the Mediterranean to the Atlantic. Several chapters focus on Iberia, but the eastern Mediterranean and Britain are also featured. Thematically, the book covers many of the research areas where zooarchaeology can provide a significant contribution. These include animal domestication, bone modifications, fishing, fowling, economic and social status, as well as adaptation and improvement. The investigation of these topics is carried out using a diversity of approaches, t...
This volume 5 of the Mesolithic Edition publishes the papers of lectures and posters presented during the conference of the AG Mesolithikum in Wuppertal in March 2017. 30 authors from Denmark, the Netherlands, Austria and Germany publish their latest research on the Mesolithic. A total of 16 contributions offer site analyses, regional and supra-regional studies as well as theoretical and methodological essays. At the end of the volume, the full publication list of the honouree Bernhard Gramsch is published.
From a modern-day perspective, it may seem odd that people should have chosen to dwell in the open salt-marsh landscape along the Wadden Sea coast. While the beauty of the salt marshes is widely acknowledged, the idea of living there seems to suggest struggle and misery. Yet the salt-marsh settlers, dwelling on their settlement mounds or terps, did not just ‘survive' or ‘get by', but actually managed to live a good life, by embracing this marshy world and its peculiarities. This collection of papers focuses on foraging, farming and food preparation in the context of the salt-marsh environment. The various contributions celebrate the career and work of Annet Nieuwhof, who has been an inspirational colleague and great friend to many of us. She passionately embraced terp research, always actively stimulating cooperation across disciplines as well as national borders. Reflecting some of Annet's wide-ranging interests, the present volume is dedicated to her in friendship and gratitude.
Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the serial to reflect this newer understanding of function-structure relationships in cellular communication. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.
Allergy is developing into one of the most prevalent diseases affecting individuals in the very early days of life. While the cause of this epidemic is still unclear, it appears that the westernized life style is playing an important role, which includes nutrition, possibly air pollution as well as hygienic conditions. While epidemiologic studies were able to narrow down these factors, basic research discovered novel mechanisms that control the organism ́s tolerance against allergens. Particularly interesting is the role of microorganisms that colonize or infect a host and thereby cause damage and immunological activation followed by sensitization or exacerbation of already existing sensitizations. However at the same time microbial activation of the immune system can help to generate a protective immunity that prevents allergen sensitization. The current book is collecting these evidences and connects epidemiologic and clinical mechanistic knowledge. Only the synthesis of this knowledge will help to find solutions to the ongoing allergy epidemic in terms of public health activities, prevention and therapy.