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Human Hybridomas and Monoclonal Antibodies
Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied. Indeed, production of murine monoclonal antibodies is now considered routine by immunologists and nonimmunologists alike. However, as heterologous proteins, mouse monoclonal antibodies have one major limitation: they are immunogenic in man and, hence, their use in vivo is severely limited. An obvious solution to this problem is to produce human hybridomas with the same techniques used for the production of rodent hybrids. Unfortunately, the history of human hybridomas has been marked b...
God in the Rainforest
In January of 1956, five young evangelical missionaries were speared to death by a band of the Waorani people in the Ecuadorian Amazon. Two years later, two missionary women--the widow of one of the slain men and the sister of another--with the help of a Wao woman were able to establish peaceful relations with the same people who had killed their loved ones. The highly publicized deaths of the five men and the subsequent efforts to Christianize the Waorani quickly became the defining missionary narrative for American evangelicals during the second half of the twentieth century. God in the Rainforest traces the formation of this story and shows how Protestant missionary work among the Waorani...
Shenandoah Valley Pioneers and Their Descendants
This is an exhaustive regional history of the parent county of nine present-day Virginia or West Virginia counties. It features several hundred detailed genealogical and biographical sketches of early families of old Frederick County. With an improved index
Monoclonal Antibodies and Functional Cell Lines
This volume serves as a follow-up to our previous book, MonoclonalAntibodies Hybridomas: A New Dimension in Biological Analyses. We continue the theme of monoclonal antibodies and their applications, attempting to cover some of the areas not covered in the previous volume. We again include an appendix de scribing methods useful to those who ar-e beginning to apply these techniques in their own laboratories. This volume will be followed by another concentrating on the combination of monoclonal antibody techniques with molecular genetic techniques to study structure/function relationships at the level of both the gene and gene product. Roger H. Kennett Kathleen B. Bechtol Philadelphia, Pennsyl...
Official Gazette of the United States Patent and Trademark Office
description not available right now.
Antibody Techniques
The applicability of immunotechniques to a wide variety of research problems in many areas of biology and chemistry has expanded dramatically over the last two decades ever since the introduction of monoclonal antibodies and sophisticated immunosorbent techniques. Exquisitely specific antibody molecules provide means of separation, quantitative and qualitative analysis, and localization useful to anyone doing biological or biochemical research. This practical guide to immunotechniques is especially designed to be easily understood by people with little practical experience using antibodies. It clearly presents detailed, easy-to-follow, step-by-step methods for the widely used techniques that exploit the unique properties of antibodies and will help researchers use antibodies to their maximum advantage. - Detailed, easy-to-follow, step-by-step protocols - Convenient, easy-to-use format - Extensive practical information - Essential background information - Helpful hints
Biomaterials Science and Tissue Engineering
Covers key principles and methodologies of biomaterials science and tissue engineering with the help of numerous case studies.
Inflammation, Advancing Age and Nutrition
The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. - Includes models of aging, including worm, mouse and human - Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health - Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition - Includes suggested nutritional interventions
The Science of Monsters
Modern audiences do not find dragons frightening. Fascinating as mythical creatures, yes, but terrifying, no. Yet, present them with a story about a virus that can kill a healthy adult in hours and they will have nightmares for weeks. The difference between the two is believability. Monsters are at their most frightening when they carry characteristics that tie them to the real world in some way. Preposterous as they might seem today, dragons were no different in ancient times. Humans long ago stumbled upon skeletons that had sharp teeth and talon-like claws. These fossils were real and some were frighteningly large. Those who looked at them could only guess at how dangerous the animals that...
Plant Biotechnology and Transgenic Plants
Contains case studies illustrating the cell culture production of pigments, flavors, and antineoplastic compounds Plant Biotechnology and Transgenic Plants covers topics that range from food to fragrances to fuel. It includes discussions of technologies and research on the engineering, synthesis, utilization, and control of primary and secondary plant metabolites such as carbohydrates, amino acids, lipids, polymers, proteins, and phytochemicals for industrial, pharmaceutical, and food and feed applications. The editors put the emphasis on recent methods in farming, plant propagation, and breeding and modern procedures to formulate more effective biopharmaceuticals.
