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The pioneering figures presented here have forged new paths for women in fields ranging from nursing, pharmacy, public health, and dentistry to general and hospital practice, hospice care, virology, surgery, and psychiatry. Their stories reveal the special obstacles they faced and overcame as women practicing in a demanding, traditionally all-male field. They also chronicle the history of medicine in the state generally since, although there was discrimination and resistance to accepting them, their accomplishments paralleled and in some instances led the development of medical practice and specialization. Using vignettes and biographical details garnered from sparse available literature, ne...
The Molecular Biology of Cancer discusses the state of progress in the molecular biology of cancer. The book describes the effects of anticancer agents on nucleolar ultrastructure; the role of chromosomes in the causation and progression of cancer and leukemia; the replication, modification, and repair of DNA. The text also describes the metabolism and utilization of messenger RNA and other high molecular weight RNA and low molecular weight nuclear RNA; the characteristics, structures, and functions of nuclear proteins; and the process of protein synthesis. Nucleotides are reviewed with regard to its biosynthesis, inhibition of synthesis, and development of resistance to inhibitors. The book further tackles the biochemical mechanisms of chemical carcinogenesis; the oncogenic viruses; and the molecular correlation concept. The text also demonstrates phenotypic variability as a manifestation of translational control; and plasmacytomas. Molecular biologists, virologists, pathologists, cell biologists, oncologists, pharmacologists, and students taking related courses will find the book useful.
The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
Human Polyomaviruses Molecular and Clinical perspectives Edited by Kamel Khalili and Gerald L. Stoner Our understanding of human polyomaviruses has evolved profoundly in the last fifteen years, creating an urgent need for an updated resource. Drs. Khalili and Stoner have collected the contributions of renowned researchers and clinicians in this cutting-edge volume. Human Polyomaviruses: Molecular and Clinical Perspectives presents in-depth analyses, comprehensive reviews, and timely assessments of recent discoveries and ongoing controversies focused on these important viral pathogens. Beginning with an historical perspective, this book covers up-to-date investigations into the molecular biol...
This book is a go-to guide for all families seeking trustworthy information about the science and safety of vaccines. Paul A. Offit and Charlotte A. Moser—scientists and parents with decades of experience—equip readers with the facts they need to navigate vaccine decisions for the whole family, from babies to elders. In straightforward prose, they offer accessible and authoritative answers to today’s most common vaccine-related questions. Offit and Moser explain how vaccines work, how they are made, and how they are tested. Chapters examine vaccine safety, ingredients, the workings of the immune system, and practical considerations from the implications of different medical conditions ...