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In September 1998, Michael J. Fox stunned the world by announcing that he had been diagnosed with Parkinson's disease - in fact, he had been secretly fighting it for seven years. In this candid book, with his trademark ironic sensibility and sense of the absurd, he tells his life story - from his childhood in western Canada to his meteoric rise in film and television and, most importantly, the years in which - with the unswerving support of his wife, family and friends - he has dealt with his illness. He talks about what Parkinson's has given him: the chance to appreciate a wonderful life and career, and the opportunity to help search for a cure and spread public awareness of the disease. He feels as if he is a very lucky man indeed.
This presentation describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands, and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic, and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resi...
With possible exception of the atomic clock, the heart may be the most perfect machine ever devised. How it develops from a simple embryonic tube is a fascinating story of biology and lends a great deal of insight into the source of heart defects that affect children and adults alike. Central to this entire lecture is the fact that the fetus resides in an aquatic environment. Oxygenated blood arrives from the placenta and deoxygenated returns to the placenta. The lungs play no role in delivering oxygen or removing carbon dioxide to or from the circulation. Thus, the fetus mainly (but not exclusively) requires a three-chambered heart rather than the fourchambered heart that we are all familia...
Histologically, muscle is conveniently divided into two groups, striated and nonstriated, based on whether the cells exhibit cross-striations in the light microscope (Figure 3). Smooth muscle is involuntary: its contraction is controlled by the autonomic nervous system. Striated muscle includes both cardiac (involuntary) and skeletal (voluntary). The former is innervated by visceral efferent fibers of the autonomic nervous system, whereas the latter is innervated by somatic efferent fibers, most of which have their cell bodies in the ventral, motor horn of the spinal cord. Smooth muscle is designed to have slow, relatively sustained contractions, while striated muscle contracts rapidly and u...
Thomas H. Olbricht grew up in Churches of Christ, has taught in several of their universities, and has given religious lectures on six continents and in most states in the United States. He has met most leaders in Churches of Christ globally. He has been active in several religious and rhetoric societies and has worked with leaders in all these organizations to bring about changes over the past sixty years. C. Clifton Black and Duane F. Watson wrote about Olbricht, "Tom Olbricht possesses a memory of elephantine proportions. Not only does he have at his fingertips the names and places and dates; better than most he understands how the study of rhetoric has flourished among, while cross-pollinating, multiple disciplines in the humanities, classics, English, speech communication, and religion."
From Simon & Schuster, The World's Money is Michael Moffitt's exploration to international banking from Bretton Woods to the brink of insolvency. For any reader looking to understand our banking system and its many failings, The World's Money is a must read and, despite, its publication date, its principles remain as relevant today as they did 30 years ago.
This book brings the insights of game professionals, DCC creators, hardware vendors, and current researchers together into a collection that focuses on the most underrepresented and critical part of game production: tools development. The first gems-type book dedicated to game tools, this volume focuses on practical, implementable tools for game de