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"If there's a pretty girl, I won't touch her!" [Previous Chapter] [Table of Contents] [Next Chapter] He was a wolf, he never let go of any of the beauties beside him, he was a mystery, from being an orphan to instantly becoming the crown prince of a mysterious organization in China, he was a god, galloping across China, shaking the world, becoming the world's sovereign, embracing endless beauties, behind the scenes, in the dark world, he became stronger and stronger, watching how he manipulated life's journey, overturning the world, writing magnificent legends.
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MW, YL and ZC were employed by Inner Mongolia Shuangqi Pharmaceutical Co.Ltd. XZ, FL, LC and ZC were employed by Shenzhen Wedge Microbiology Research Co.Ltd.
Biomolecular sequence comparison is the origin of bioinformatics. This book gives a complete in-depth treatment of the study of sequence comparison. A comprehensive introduction is followed by a focus on alignment algorithms and techniques, proceeded by a discussion of the theory. The book examines alignment methods and techniques, features a new issue of sequence comparison - the spaced seed technique, addresses several new flexible strategies for coping with various scoring schemes, and covers the theory on the significance of high-scoring segment pairs between two unalignment sequences. Useful appendices on basic concepts in molecular biology, primer in statistics and software for sequence alignment are included in this reader-friendly text, as well as chapter-ending exercise and research questions A state-of-the-art study of sequence alignment and homology search, this is an ideal reference for advanced students studying bioinformatics and will appeal to biologists who wish to know how to use homology search tools.
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, thus enabling large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, metabolic pathways, and gene expression profiles of normal and diseased tissues are rapidly being generated for human and model organisms. Bioinformatics is therefore gaining importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of the genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industry practitioners at the 6th Asia-Pacific Bioinformatics Conference held in Kyoto, Japan, in January 2008.
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Publisher’s note: This is a 2nd edition due to an article retraction
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