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-There is an acceleration in prion disease research because of the spread of mad cow disease. -This book covers in vitro, cellular, and animal models adapted for the study of TSEs. -Includes bio-saftey procedures.
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This book is a printed edition of the Special Issue "PrPSc prions: state of the art" that was published in Pathogens
In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders. Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
Looking at the Latin American liberal project during the century of postindependence, this collection of original essays draws attention to an underappreciated dilemma confronting liberals: idealistic visions and fiscal restraints. Liberals, Politics, and Power focuses on the inventiveness of nineteenth-century Latin Americans who applied liberal ideology to the founding and maintenance of new states. The impact of liberalism in Latin America, the contributors show, is best understood against the larger backdrop of struggles that pitted regional demands against the pressures of foreign finance, a powerful church against a decentralized state, and aristocratic desire to retain privilege again...
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