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Epilepsy
Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website. More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and...
Jasper's Basic Mechanisms of the Epilepsies
H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous e...
Graphical Models
This book exemplifies the interplay between the general formal framework of graphical models and the exploration of new algorithm and architectures. The selections range from foundational papers of historical importance to results at the cutting edge of research. Graphical models use graphs to represent and manipulate joint probability distributions. They have their roots in artificial intelligence, statistics, and neural networks. The clean mathematical formalism of the graphical models framework makes it possible to understand a wide variety of network-based approaches to computation, and in particular to understand many neural network algorithms and architectures as instances of a broader...
Long-term Potentiation
Following the successful format of the first volume on long- term potentiation -- a leading candidate for the neuronal basis of learning and memory -- Volume 2 brings together the most recent data and hypotheses by top neuroscientists regarding the mechanisms of this phenomenon and of long-term depression (LTD). The book is divided into several sections covering different aspects of the field ranging from molecular mechanisms of plasticity to computational neurobiology. It revisits some of the major points covered in Volume 1, updating them in this fast-moving field. It also introduces several new issues that have arisen since then. Of the many possible new topics that could have been added, the editors have focused on retrograde messengers and the mechanisms and functions of LTP and LTD because they are the subject of much interest, research, and controversy. The section on retrograde messengers deals primarily with nitric oxide.
Disorders of Brain and Mind: Volume 1
Great advances have been made in recent years toward a better understanding of the healthy brain and the physical basis of psychiatric disorder. This text brings together contributions from leading international authorities to provide a timely and multidisciplinary overview of this fast developing area. This book provides broad coverage ranging from epilepsy and schizophrenia to basal ganglia disorder and brain lesions. In many cases, a clinically oriented chapter is paired with one that describes the basic science that underpins it, and considerable attention is given to the impact of new technologies, such as structural and functional neuroimaging. This book highlights the basic pathophysiological mechanisms of multifaceted clinical manifestations to provide a valuable review of current neuropsychiatry. It will be welcomed by clinicians, researchers, and students alike from neuroscience to neuropsychology and psychiatry.
The Human Brain and Its Disorders
The Human Brain and its Disorders offers an engaging and accessible introduction to the human brain and the human nervous system, what happens when normal neural function is lost, and how resulting disorders can be treated, aimed specifically for a non-medical audience.
Models of Seizures and Epilepsy
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Modern Concepts of Focal Epileptic Networks
This volume of International Review of Neurobiology concentrates on modern concepts of focal epileptic networks. The volume addresses specific topics such as seizures (including transition and termination), limbic networks, alteration of metabolism, and neocortical focus and malformation of cortical development, among others. Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews, and thematic volumes that focus on recent progress in a specific area of neurobiology research. - Our knowledge about the mechanisms involved in pathophysiology of epilepsy has rapidly expanded during last decade - This special volume brings overview about modern concepts of epileptic focus organization and about the altered neural network dynamics which results in propensity of the brain tissue to generate spontaneous and repeated seizures
Introduction to Epilepsy
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.
