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Software Engineering
The capability to design quality software and implement modern information systems is at the core of economic growth in the 21st century. This book aims to review and analyze software engineering technologies, focusing on the evolution of design and implementation platforms as well as on novel computer systems.
Attorneys and Agents Registered to Practice Before the U.S. Patent and Trademark Office
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Development of Therapeutic Agents Handbook
A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives professionals a basic tool to facilitate research and development within this challenging process. This comprehensive text brings together, in one resource, a compendium of concepts, approaches, methodologies, and limitations that need to be considered in the formulation of therapeutic agents across a range of therapeutic fields. Both a reference and a call to action for the pharmaceutical industry, Development of Therapeutic Agent...
Register of Commissioned and Warrant Officers of the United States Navy and Reserve Officers on Active Duty
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Early Life Nutrition and Future Health
Inequity starts before birth and is programmed in part by nutritional exposures. If these exposures occur around the time of conception, during pregnancy, and/or in infancy or childhood (all critical periods of development) they may alter a child’s health trajectory and impact risk for impaired cognition and learning, and cardiometabolic, immune, and neuropsychiatric diseases and disorders. This Special Issue on “Early Life Nutrition and Future Health” has the following aims: 1) understand the origins of offspring health inequities from an early nutritional perspective; 2) uncover new insights into the environmental, biological, and social mechanisms that underpin these health outcomes...
Systems Biology
Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of th...
Molecular mechanisms and physiology of disease
In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory an...
Software Process Improvement
This book constitutes the refereed proceeding of the 13th European Software Process Improvement Conference, EuroSPI 2006, held in Joensuu, Finland in October 2006. The 18 revised full papers presented were carefully reviewed and selected from 62 submissions.
Weight Management
The physiological or pathological variations in the amount or mass of each component of body weight can lead to an increase or a decrease in total body weight, with a potential risk of increased morbidity and mortality. This book presents an overview of current knowledge about different types of body weight changes, with a special emphasis on obesity.
