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A hub for barefoot bohemians and glamorous goddesses, Tulum is a Mayan hideaway that perfectly distills the gypset lifestyle. An off-grid escape for nomadic creatives, it is a playground for spirituality and community. This tiny, idyllic eight-mile strip of sand on Mexico’s Yucatán Peninsula is tucked between a tropical jungle, Mayan ruins, and the Sian Ka’an biosphere: It’s a heady vortex. Tulum’s isolated and breathtakingly beautiful environment also makes it the perfect place for those craving a deeper connection with themselves, others, and nature. Seekers (sun, spiritual, and otherwise) pilgrimage to this beach settlement in droves to join this avant-garde template for a new bohemian lifestyle that prioritizes healing, eco-friendly practices and organic cuisine. The boho-chic crowd’s home away from home, Tulum is a rare and successful modern experiment in both consciousness and sophistication, bolstered by its down-to-earth hotels, mesmerizing cenotes, and lush backdrop.
This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.
The expression of uncertainty in measurement poses a challenge since it involves physical, mathematical, and philosophical issues. This problem is intensified by the limitations of the probabilistic approach used by the current standard (the GUM Instrumentation Standard). This text presents an alternative approach. It makes full use of the mathematical theory of evidence to express the uncertainty in measurements. Coverage provides an overview of the current standard, then pinpoints and constructively resolves its limitations. Numerous examples throughout help explain the book’s unique approach.
This volume details protocols on rationale design of therapeutic siRNA molecules and its encapsulation with smart vehicles to overcome the barriers to an effective administration in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Design and Delivery of SiRNA Therapeutics aims to ensure successful results in the further study of this vital field. This volume details protocols on rationale design of therapeutic ...
Adam Sabir has discovered the missing quatrains of Nostradamus, and the events they foretell are coming true. But there's one prophecy he can't fully decipher, and it warns of the imminent arrival of the Third Antichrist. Sabir's every move is the Corpus Maleficus, an ancient cabal devoted to serving the Antichrist. Disfigured, orphaned, groomed for cruelty and violence, they are prepared to do anything to stop him. As Sabir puzzles over the riddle, a descendant of the Mayans embarks on a dangerous journey. He must deliver a sacred codex to the Palace of the Masks. Only then can the secret of Nostradamus' prophecy be revealed...
This book, first published in 1933, examines the life and achievements of Henry Adams, the American historian and political journalist. It looks at his youth and early development of his ideas, and goes on to look at his time as a diplomat, historian and journalist – and his impact upon American political and intellectual life.
A practical guide for the diagnostic surgical pathologist, this new edition of Biopsy Interpretation of the Breast presents the diverse spectrum of pathologic alterations that occur in the breast in a manner analogous to that in which they are encountered in daily practice. Lesions are grouped together according to their histologic patterns rather than by the traditional benign-malignant categorization in order to simulate the way pathologists face these lesions as they examine microscopic slides on a daily basis. The role of adjunctive studies in solving diagnostic problems in breast pathology is emphasized where appropriate. In addition, the clinical significance and impact on patient management of the various diagnoses are discussed and key clinical and management points highlighted.