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Dyke Swarms of the World: A Modern Perspective
Continuing the tradition of International Dyke Conference, this book is largely based on contributions from the IDC7 but also includes some chapters by invitation. It focuses on mafic dyke swarms and related associations: e.g. links with sills, kimberlites, syenites, carbonatites, and volcanics, discussing the following themes: (i) regional maps/reviews of dyke swarms and related units, (ii) the role of giant dyke swarms in the reconstruction of supercontinents/paleocontinents, (iii) mapping of dykes using remote sensing techniques, (iv) geochronology of dyke swarms, (v) petrology, geochemistry and petrogenesis of dykes, (vi) emplacement mechanism of dykes, (vii) dyke swarms and planetary bodies, and (viii) links to mineralization and resources.
Superplumes: Beyond Plate Tectonics
This abundantly illustrated book provides a concise overview of our understanding of the entire mantle, its evolution since early differentiation and the consequences of superplumes for earth surface processes. The book’s balanced authorship has produced a state-of-the-science report on the emerging concept of superplumes. This presents a new concept to explain catastrophic events on Earth through geologic time.
Plates vs Plumes
Since the advent of the mantle plume hypothesis in 1971, scientists have been faced with the problem that its predictions are not confirmed by observation. For thirty years, the usual reaction has been to adapt the hypothesis in numerous ways. As a result, the multitude of current plume variants now amounts to an unfalsifiable hypothesis. In the early 21st century demand became relentless for a theory that can explain melting anomalies in a way that fits the observations naturally and is forward-predictive. From this the Plate hypothesis emerged–the exact inverse of the Plume hypothesis. The Plate hypothesis attributes melting anomalies to shallow effects directly related to plate tectonic...
Rational Basis for Clinical Translation in Stroke Therapy
Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs th
Dyke Swarms - Time Markers of Crustal Evolution
Dyke swarms are remnants of large igneous provinces, and are pointers of continental break-up events, as well as indicators for ancient continental reconstructions. These global geodynamic aspects are of crucial significance in tectonics, and with recent developments in high-precision age, dating it has become possible to enter these short-lived ma
Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders
This new volume of Advances in Pharmacology presents pharmacology of the blood brain barrier, focusing on targeting CNS disorders. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. - Contributions from the best authors in the field - An essential resource for pharmacologists, immunologists, and biochemists
The Crust
The Treatise on Geochemistry is the first work providing a comprehensive, integrated summary of the present state of geochemistry. It deals with all the major subjects in the field, ranging from the chemistry of the solar system to environmental geochemistry. The Treatise on Geochemistry has drawn on the expertise of outstanding scientists throughout the world, creating the reference work in geochemistry for the next decade. Each volume consists of fifteen to twenty-five chapters written by recognized authorities in their fields, and chosen by the Volume Editors in consultation with the Executive Editors. Particular emphasis has been placed on integrating the subject matter of the individual chapters and volumes. Elsevier also offers the Treatise on Geochemistry in electronic format via the online platform ScienceDirect, the most comprehensive database of academic research on the Internet today, enhanced by a suite of sophisticated linking, searching and retrieval tools.
Mantle Convection for Geologists
Mantle convection is the fundamental agent driving many of the geological features observed at the Earth's surface, including plate tectonics and plume volcanism. Yet many Earth scientists have an incomplete understanding of the process. This book describes the physics and fluid dynamics of mantle convection, explaining what it is, how it works, and how to quantify it in simple terms. It assumes no specialist background: mechanisms are explained simply and the required basic physics is fully reviewed and explained with minimal mathematics. The distinctive forms that convection takes in the Earth's mantle are described within the context of tectonic plates and mantle plumes, and implications are explored for geochemistry and tectonic evolution. Common misconceptions and controversies are addressed - providing a straightforward but rigorous explanation of this key process for students and researchers across a variety of geoscience disciplines.
Monoclonal Hybridoma Antibodies
The first section of this volume is aimed to provide a comprehensive review of the many varied and often empirically derived techniques and procedures currently in use to produce monoclonal hybridoma cell lines and to characterize the antibodies secreted. The goal has been achieved with the chapter contributed by Zola and Brookes who, as each step in the process of hybridoma production and antibody characterisation is reviewed, have provided an experimental procedure found to be satisfactory in their laboratory.The second section of this volume is designed to provide a review of areas in which monoclonal hybridoma antibodies have been of particular advantage. This is a rapidly advancing field which could not be thoroughly reviewed in a single volume.
