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“Go into partnership with nature; she does more than half the work and asks none of the fee.” - Martin H. Fisher. Nature has undertaken an immense amount of work throughout evolution. The evolutionary process has provided a power of information that can address key questions such as - Which immune molecules and pathways are conserved across species? Which molecules and pathways are exploited by pathogens to cause disease? What methods can be broadly used or readily adapted for wild immunology? How does co-infection and exposure to a dynamic environment affect immunity? Section 1 addresses these questions through an evolutionary approach. Laboratory mice have been instrumental in dissecti...
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Current Therapy in Medicine of Australian Mammals provides an update on Australian mammal medicine. Although much of the companion volume, Medicine of Australian Mammals, is still relevant and current, there have been significant advances in Australian mammal medicine and surgery since its publication in 2008. The two texts together remain the most comprehensive source of information available in this field. This volume is divided into two sections. The first includes comprehensive chapters on general topics and topics relevant to multiple taxa. Several new topics are presented including: wildlife health in Australia and the important role veterinarians play in Australia’s biosecurity syst...
A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of cont...
2019 PEN/E.O. Wilson Literary Science Writing Award Finalist "Science book of the year"—The Guardian One of New York Times 100 Notable Books for 2018 One of Publishers Weekly's Top Ten Books of 2018 One of Kirkus's Best Books of 2018 One of Mental Floss's Best Books of 2018 One of Science Friday's Best Science Books of 2018 “Extraordinary”—New York Times Book Review "Magisterial"—The Atlantic "Engrossing"—Wired "Leading contender as the most outstanding nonfiction work of the year"—Minneapolis Star-Tribune Celebrated New York Times columnist and science writer Carl Zimmer presents a profoundly original perspective on what we pass along from generation to generation. Charles Dar...
Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. This volume is focused on immunopathology of cancers. The interactions between cancerous cells and various components of the innate and adaptive immune system are fully described. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the most recent research and new developments in the field. Over the past decade, understanding of the interactions between the immune system and cancerous cells has increased markedly, leading to the development of combinatorial immunotherapeutic strategies to combat cancer. This translational, clinically oriented book will be of special value to clinical immunologists, hematologists and oncologists.
DNA is the essence of life and the original ‘big data’. New technologies are allowing scientists to access and make sense of this information like never before, and they are using it to solve the world’s greatest environmental challenges. Applied Environmental Genomics synthesises the latest and most exciting uses of genomic technologies for environmental science and management. With an emphasis on diversity of applications and real-world demonstrations, leading researchers have contributed detailed chapters on innovative approaches to obtaining critical management-relevant information about the natural world. These chapters are complemented by perspective sections written by environmental managers who describe their experiences using genomics to support evidence-based decisions. Ideal for students, researchers and professionals working in natural resource management and policy, Applied Environmental Genomics is a comprehensive introduction to a fast-moving field that is transforming the practice of environmental management, with profound relevance to industry, government and the public.
Encyclopedia of Immunobiology, Five Volume Set provides the largest integrated source of immunological knowledge currently available. It consists of broad ranging, validated summaries on all of the major topics in the field as written by a team of leading experts. The large number of topics covered is relevant to a wide range of scientists working on experimental and clinical immunology, microbiology, biochemistry, genetics, veterinary science, physiology, and hematology. The book is built in thematic sections that allow readers to rapidly navigate around related content. Specific sections focus on basic, applied, and clinical immunology. The structure of each section helps readers from a range of backgrounds gain important understanding of the subject. Contains tables, pictures, and multimedia features that enhance the learning process In-depth coverage allows readers from a range of backgrounds to benefit from the material Provides handy cross-referencing between articles to improve readability, including easy access from portable devices
A major symposium on macropods (kangaroos, wallabies and rat-kangaroos), sponsored by the Australian Mammal Society, was held in July 2006 at the University of Melbourne. It brought together the many recent advances in the biology of this diverse group of mammals and looked at: structure and function; neglected macropods; population biology; and macropod management. A total of 78 authors have contributed 34 chapters to the book, which concentrates on new developments in macropod biology, including topics such as genomics, landscape ecology, endangered species and fertility control.
An exploration of why people all over the world love to engage in pain on purpose--from dominatrices, religious ascetics, and ultramarathoners to ballerinas, icy ocean bathers, and sideshow performers Masochism is sexy, human, reviled, worshipped, and can be delightfully bizarre. Deliberate and consensual pain has been with us for millennia, encompassing everyone from Black Plague flagellants to ballerinas dancing on broken bones to competitive eaters choking down hot peppers while they cry. Masochism is a part of us. It lives inside workaholics, tattoo enthusiasts, and all manner of garden variety pain-seekers. At its core, masochism is about feeling bad, then better—a phenomenon that is ...