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Modeling Excitable Tissue
This open access volume presents a novel computational framework for understanding how collections of excitable cells work. The key approach in the text is to model excitable tissue by representing the individual cells constituting the tissue. This is in stark contrast to the common approach where homogenization is used to develop models where the cells are not explicitly present. The approach allows for very detailed analysis of small collections of excitable cells, but computational challenges limit the applicability in the presence of large collections of cells.
Differential Equations for Studies in Computational Electrophysiology
This open access text aims at giving you the simplest possible introduction to differential equations that are used in models of electrophysiology. It covers models at several spatial and temporal scales with associated numerical methods. The text demonstrates that a very limited number of fundamental techniques can be used to define numerical methods for equations ranging from ridiculously simple to extremely complex systems of partial differential equations. Every method is implemented in Matlab and the codes are freely available online. By using these codes, the reader becomes familiar with classical models of electrophysiology, like the cable equation, the monodomain model, and the bidomain model. But modern models that have just started to gain attention in the field of computational electrophysiology are also presented. If you just want to read one book, it should probably not be this one, but if you want a simple introduction to a complex field, it is worth considering the present text.
Connecting Sarcomere Protein Mutations to Pathogenesis in Myopathies
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Protecting Your Children Online
As parents, our main job is to protect our children. These days, protection from includes not only the individuals we can see but, also, the individuals that we cannot see – yet who wish to harm our children. And with the growth of social networking and social media parents are often unaware of their child’s interactions on the internet. Protecting Your Children Online: What You Need to Know About Online Threats to Your Children introduces the crimes that can occur in cyberspace, as well as procedures for reporting and obtaining assistance in the event of victimization. Throughout Kimberly McCabe addresses several types of cyber crimes, ranging from child pornography and solicitation to ...
Railroaded: The Transcontinentals and the Making of Modern America
A Finalist for the Pulitzer Prize "A powerful book, crowded with telling details and shrewd observations." —Michael Kazin, New York Times Book Review The transcontinental railroads were the first corporate behemoths. Their attempts to generate profits from proliferating debt sparked devastating economic panics. Their dependence on public largesse drew them into the corridors of power, initiating new forms of corruption. Their operations rearranged space and time, remade the landscape of the West, and opened new ways of life and work. Their discriminatory rates sparked a new antimonopoly politics. The transcontinentals were pivotal actors in the making of modern America, but the triumphal myths of the golden spike, Robber Barons larger than life, and an innovative capitalism all die here. Instead we have a new vision of the Gilded Age, often darkly funny, that shows history to be rooted in failure as well as success.
