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Development of the Hypothalamus
The involvement of key factors operating independently or in cooperation with others contributes to physical and physiological mechanisms to help engineer a vertebrate hypothalamus. The actions of these key factors influence developmental mechanisms including neurogenesis, cell migration, cell differentiation, cell death, axon guidance, and synaptogenesis. On a molecular level, there are several ways to categorize the actions of factors that drive brain development. These range from the actions of transcription factors in cell nuclei that regulate the expression of developmental genes, to external factors in the cellular environment that mediate interactions and cell placements, and to effector molecules that contribute to signaling from one cell to another. Sexual dimorphism is a hallmark of the vertebrate hypothalamus that may arise as a direct consequence of hormone actions or gene actions. These actions may work through any of the mechanisms outlined above. Given the arrangement of cells in groups within the hypothalamus, cell migration may be one particularly important target for early molecular actions that help build the bases for appropriate functions.
Top Dog
Compete better... In a competitive situation our bodies can experience the same level of stress hormones as jumping out of a plane. Competition is often the key to outstanding achievement. But what is it that makes the difference between rising to the challenge and buckling under pressure? Using groundbreaking studies in diverse scientific fields, Bronson and Merryman demonstrate that understanding how to harness our competitive fire means we can perform our best – whether the contest is sporting, academic or in the workplace. Why are men typically prepared to gamble on long or even stupid odds and women aren’t? Why do some less talented students consistently outperform their smarter cla...
Developmental Neuroendocrinology
In this book, experts in the field discuss the latest research in developmental neuroendocrinology. Given that the hypothalamus is the center of neuroendocrine activity, the reader will learn about the molecular specification of hypothalamic cells, developmental modulators and epigenetic factors influencing hypothalamic development, and the development of neuroendocrine circuits. Each chapter provides a concise review of the current and future perspectives in developmental neuroendocrinology. Important insights into state-of-the-art techniques applied to functional circuit tracking, lineage tracing of hypothalamic cells, and the identification of genes altered through epigenetic mechanisms a...
Proceedings of the National Academy of Sciences of the United States of America
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Jesus and Women - Bible Study Book
Join biblical culturalist Krisi McLelland as she takes you back to Jesus' first-century world, explaining the historical and cultural climate of His day. This 7-session Bible study is a look at several of Jesus' interactions with women.
The Gospel on the Ground - Bible Study Book with Video Access
Come along with biblical culturalist Kristi McLelland as she unpacks the life of the early church in the book of Acts and shows us that the kingdom of God is always on the move, always looking outward to bring meaning and joy to a world searching for true fulfillment and hope. Explore the call of Jesus to His disciples then and to us today. See how God's Word can sustain us even in the most difficult of times and embrace the transformative grace we experience as children of God in His kingdom of celebration. Features: Leader helps to guide questions and discussions within small groups 6 weeks of personal study to be completed between the 7 group sessions Access to 7 teaching videos, approximately 50-60 minutes per session, available by redeeming a code printed in the back of the study book Benefits: Gain deeper insight into the biblical world, including fresh perspective on familiar Bible stories. Ignite a passion to be on mission by examining the work of the early church. Find deep purpose and meaning at the table of God. Find joy in the communal aspect of faith. See how God's redemptive purposes are unstoppable in the Book of Acts.
Better Late Than Never
It's funny how life never pans out the way you'd expect.I always knew that something wasn't right, that some part of my inside didn't match my outside. What I didn't know then is that I'm transgender, a realization that took a lifetime to fully unpack and understand. And to embrace. Growing up in Michigan I started off sheltered with no idea of what lay over the horizon, but serving in the navy opened my eyes to what possibilities might be within my grasp. I encountered many forks in the road, sometimes I made the right choice, sometimes my decisions were terribly wrong. But in the end, they led me here, to finally embracing who and what I am, and discovering the joy that can only come from living as your authentic self.
