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Esta obra é uma adaptação da minha dissertação de mestrado em formato de livro que teve como objeto de estudo os fundamentos pedagógicos na Organização do Trabalho Pedagógico (OTP) dos professores de Educação Física nas séries finais do ensino fundamental na Rede Municipal de Castanhal-PA. Neste sentido, o livro analisa os fundamentos presentes na OTP dos professores de Educação Física das séries finais do ensino fundamental na Rede Municipal de Castanhal-PA. No que se refere à formação, a investigação mostrou que a maioria dos professores do Município de Castanhal possui pós-graduação em áreas fora do âmbito educacional e trabalha em outras localidades, acumuland...
There are alarming reports of new and emerging microbial diseases. The recent emergence of COVID-19 is a burning example that has attracted global attention. Not only this, the development of multidrug resistance in microbes is frightening and thus the available antibiotics have been ineffective. Considering these facts, there is a pressing need to develop effective treatment options that are eco-friendly, biobased, and cost-effective. The present book covers the natural/bio-based products from plants, mushrooms and microbes that can be used against different microbial diseases caused by viruses, bacteria and fungi. This book would be an essential reading for students, researchers and people from pharma industries. Key features: • Describes the biobased natural products to combat microbial diseases. • Examines the antimicrobial potential of mushrooms, endophytes and secondary metabolites. • Discusses the role of defensins and terpenes in microbial diseases. • Incorporates natural products from the Amazon for treating microbial diseases.
The significantly expanded and updated new edition of a widely used text on reinforcement learning, one of the most active research areas in artificial intelligence. Reinforcement learning, one of the most active research areas in artificial intelligence, is a computational approach to learning whereby an agent tries to maximize the total amount of reward it receives while interacting with a complex, uncertain environment. In Reinforcement Learning, Richard Sutton and Andrew Barto provide a clear and simple account of the field's key ideas and algorithms. This second edition has been significantly expanded and updated, presenting new topics and updating coverage of other topics. Like the fir...
The mechanistic target of rapamycin (mTOR) is a major signaling intermediary that coordinates favorable environmental conditions with cell growth. Indeed, as part of two functionally distinct protein complexes, named mTORC1 and mTORC2, mTOR regulates a variety of cellular processes, including protein, lipid, and nucleotide synthesis, as well as autophagy. Over the last two decades, major molecular advances have been made in mTOR signaling and have revealed the complexity of the events implicated in mTOR function and regulation. In parallel, the role of mTOR in diverse pathological conditions has also been identified, including in cancer, hamartoma, neurological, and metabolic diseases. Through a series of articles, this book focuses on the role played by mTOR in cellular processes, metabolism in particular, and highlights a panel of human diseases for which mTOR inhibition provides or might provide benefits. It also addresses future studies needed to further characterize the role of mTOR in selected disorders, which will help design novel therapeutic approaches. It is therefore intended for everyone who has an interest in mTOR biology and its application in human pathologies.
This book brings together specialized information on modern aspects of applied microbiology in pest management. In the last few decades, the humans have witnessed major advancements in Life Sciences, as a result several new and powerful tools and techniques have evolved. This has led to great advancements in microbial nutrition, genetics and their application in different fields. In modern era of biotechnology, the microbes have provided solutions to many of the human problems and necessities and thus serve as human and farmers’ friends. The microbes have proved to be successful tools for the pest management. Similarly, there has been much advancement in the field of molecular biology, whe...
"Biochar is the carbon-rich product when biomass (such as wood, manure, or crop residues) is heated in a closed container with little or no available air. It can be used to improve agriculture and the environment in several ways, and its stability in soil and superior nutrient-retention properties make it an ideal soil amendment to increase crop yields. In addition to this, biochar sequestration, in combination with sustainable biomass production, can be carbon-negative and therefore used to actively remove carbon dioxide from the atmosphere, with major implications for mitigation of climate change. Biochar production can also be combined with bioenergy production through the use of the gase...
Textbook and Color Atlas of Traumatic Injuries to the Teeth, Fifth Edition encompasses the full scope of acute dental trauma, including all aspects of interdisciplinary treatment. This new edition embraces the significant advances made in the subject of dental traumatology since the publication of the previous edition in 2007. Thoroughly updated throughout, it includes eight new chapters, including one chapter focused on the development of bioengineered teeth and another on clinical regenerative endodontics. Providing the theoretical background behind the clinical applications, the text is supplemented by a step-by-step online guide to procedures at www.dentaltraumaguide.org. The book is als...