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Novel clinical applications of extracellular vesicles
During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particul...
A New Ireland
It’s not your father’s Ireland. Not anymore. A story of modern revolution in Ireland told by the founder of IrishCentral, Irish America magazine, and the Irish Voice newspaper. In a May 2019 countrywide referendum, Ireland voted overwhelmingly to make abortion legal; three years earlier, it had done the same with same-sex marriage, becoming the only country in the world to pass such a law by universal suffrage. Pope Francis’s visit to the country saw protests and a fraction of the emphatic welcome that Pope John Paul’s had seen forty years earlier. There have been two female heads of state since 1990, the first two in Ireland’s history. Prime Minister Leo Varadkar, an openly gay ma...
If Only
On Boxing Day 1964 10-year-old Lesley Ann Downey left home to go to the fair. Her older brother, Terry did not go with her because he was ill with flu. Not accompanying her on that fateful day would haunt Terry for the rest of his life. Lesley was abducted by Moors murderers, Ian Brady and Myra Hindley. This is their heart-breaking story, told by Terry. This fascinating and tragic story also includes family photographs and letters from Ian Brady and Myra Hindley.
My New Roots
Holistic nutritionist and highly-regarded blogger Sarah Britton presents a refreshing, straight-forward approach to balancing mind, body, and spirit through a diet made up of whole foods. Sarah Britton's approach to plant-based cuisine is about satisfaction--foods that satiate on a physical, emotional, and spiritual level. Based on her knowledge of nutrition and her love of cooking, Sarah Britton crafts recipes made from organic vegetables, fruits, whole grains, beans, lentils, nuts, and seeds. She explains how a diet based on whole foods allows the body to regulate itself, eliminating the need to count calories. My New Roots draws on the enormous appeal of Sarah Britton's blog, which strike...
Springer Handbook of Marine Biotechnology
This Springer Handbook provides, for the first time, a complete and consistent overview over the methods, applications, and products in the field of marine biotechnology. A large portion of the surface of the earth (ca. 70%) is covered by the oceans. More than 80% of the living organisms on the earth are found in aquatic ecosystems. The aquatic systems thus constitute a rich reservoir for various chemical materials and (bio-)chemical processes. Edited by a renowned expert with a longstanding experience, and including over 60 contributions from leading international scientists, the Springer Handbook of Marine Biotechnology is a major authoritative desk reference for everyone interested or wor...
Lexicon of Geologic Names of the United States (including Alaska).
Issue identified as 1935 covers names used through Dec. 1935.
